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Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities

已完结 10 由 Luke 发布于 2025/2/14 11:37:51
DOI:10.1038/s41588-023-01515-7
 作者：Liang Chang,?Nancy Y. Jung,?Adel Atari,?Diego J. Rodriguez,?Devishi Kesar,?Tian-Yu Song,?Matthew G. Rees,?Melissa Ronan,?Ruitong Li,?Paloma Ruiz,?Saireudee Chaturantabut,?Takahiro Ito,?Laurens M. van
文献类型：期刊论文
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NatureNature
Abstract：The paradigm of cancer-targeted therapies has focused largely on inhibition of critical pathways in cancer. Conversely, conditional activation of signaling pathways as a new source of select
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