Pharmaceutical Science Advances

Computational screening of Sophora flavescens phytochemicals as potential aromatase inhibitors: Molecular docking, ADMET, Network pharmacology, Molecular dynamics simulation, and DFT studies

Pub Date : 2026-01-20 DOI: 10.1016/j.pscia.2026.100108 Laiba Rashid , Jarin Tasnim , Md Mehedi Hasan , Hammad Ismail , Khan Rajib Hossain , Sarnop Sarker , Ayesha Younas , Muhammad Mujtaba , Mohammad Taufiq Alam

Metabolomic profiling of Musanga cecropioides leaf extract reveals cytotoxic mechanisms in MCF-7 breast cancer cells

Pub Date : 2025-11-25 DOI: 10.1016/j.pscia.2025.100107 Olubusola O. Olaleye , Dong-Hyun Kim , Keith A. Spriggs

Graminoides A-D, antibacterial cyclic octaketides from the desert-derived Streptomyces

Pub Date : 2025-11-21 DOI: 10.1016/j.pscia.2025.100106 Xianggang Hu , Shengliang Zhao , Wenqing Yan , Qian Zhang , Jie Huang , Lei Dong , Chunhua Lu , Wenjun Li