Resistance Mechanisms

Abstract A43: Increased cyclin A expression is associated with antiprogestin resistance and progesterone receptor isoforms ratio in experimental models of breast cancer

Pub Date : 2018-08-01 DOI: 10.1158/1557-3125.ADVBC17-A43 Marina Ayre, M. Bilinski, B. Jacobsen, C. Lanari, V. Fabris

Abstract A37: Combined targeting of estrogen receptor alpha and nuclear transport pathways remodels metabolic pathways to induce apoptosis and overcome tamoxifen resistance

Pub Date : 2018-08-01 DOI: 10.1158/1557-3125.ADVBC17-A37 E. K. Cotul, Kinga Wrobel, L. Yosef, Zeynep Madak-Erdogan

Abstract B35: Palbociclib treatment activates FAK and use of palbociclib in combination with the FAK inhibitor PF-562,271 enhances antitumor activity in ER-positive breast cancer cells

Pub Date : 2018-08-01 DOI: 10.1158/1557-3125.ADVBC17-B35 Grant A. Howe, V. Allen, C. Addison