medRxiv - Allergy and Immunology

A GWAS of ACE Inhibitor-Induced Angioedema in a South African Population.

Pub Date : 2024-09-15 DOI: 10.1101/2024.09.13.24313664 Jacquiline Wangui Mugo, Cascia Day, Ananyo Choudhury, Maria Deetlefs, Robert Freercks, Sian Geraty, Angelica Panieri, Christian Cotchbos, Melissa Ribeiro, Adelein Engelbrecht, Lisa K. Micklesfield, Michèle Ramsay, Sarah Pedretti, Jonny Peter

Patterns and functional consequences of antibody speciation in maternal-fetal transfer of coronavirus-specific humoral immunity

Pub Date : 2024-09-13 DOI: 10.1101/2024.09.12.24313591 Andrew P Hederman, Hannah M Brookes, Harini Natarajan, Leo Heyndrickx, Kevin K. Arien, Joshua A Weiner, Amihai Rottenstreich, Gila Zarbiv, Dana Wolf, Tessa Goetghebuer, Arnaud Marchant, Margaret E Ackerman

A novel UNC93B1 gain-of-function mutation leads to TLR7 and TLR8 hyperactivation and systemic lupus erythematosus

Pub Date : 2024-09-13 DOI: 10.1101/2024.09.11.24313360 Xu Han, RuoRan Wang, Seza Ozen, Qintao Wang, Wei Dong, Yi Zeng, Ouyuan Xu, Seher Şenar, Li Guo, Ying Gu, Huanming Yang, Xiaomin Yu, Panfeng Tao, Qing Zhou