Molecular Therapy - Methods & Clinical Development

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Evaluation of a Rapid Multi-Attribute Combinatorial High-Throughput UV-Vis/DLS/SLS Analytical Platform for rAAV Quantification and Characterization

Pub Date : 2024-07-01 DOI: 10.1016/j.omtm.2024.101298 Xueyuan Liu, Riffard Jean-Gilles, Julia Baginski, Christina Cai, Ruilan Yan, Lili Zhang, Kevin Lance, Johannes C.M. van der Loo, Beverly L. Davidson

Suppression of toxic transgene expression by optimized artificial miRNAs increases AAV vector yields in HEK-293 cells

Pub Date : 2024-06-01 DOI: 10.1016/j.omtm.2024.101280 Gina Blahetek, Christine Mayer, Johannes Zuber, Martin Lenter, Benjamin Strobel

Biomanufacturing in gene and cell therapy

Pub Date : 2024-06-01 DOI: 10.1016/j.omtm.2024.101261 Daniel Stone, Xiuyang Wang, Mohamed Abou-el-Enein

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Molecular Therapy - Methods &amp; Clinical Development