Drug Metabolism and Pharmacokinetics

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Clinical pharmacokinetic characteristics of Jaktinib in subjects with hepatic impairment in a phase I trial

Pub Date : 2024-07-01 DOI: 10.1016/j.dmpk.2024.101030 Manna Zhao, Hua Zhang, Sheng Ma, Shuqing Gong, Cheng Wei, Liyan Miao, Weifeng Zhao

Characterization of plasma vonoprazan and CYP3A activity using its endogenous marker and genetic variants in patients with digestive system disorders

Pub Date : 2024-07-01 DOI: 10.1016/j.dmpk.2024.101027 Kenta Sakaguchi, Takafumi Naito, Kohei Hoshikawa, Yukari Miyadera, Hironari Tanaka, Emi Nakatsugawa, Takahisa Furuta, Ken Sugimoto, J. Kawakami

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