bioRxiv : the preprint server for biology

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MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis.

Pub Date : 2026-02-03 DOI: 10.64898/2026.01.12.697845 Sunehera Sarwat, Rosa Alen, Zhiyi Wu, Chuyue Zhang, Michael Paszek, MingMing Yang, Giada Ostinelli, Alina Mihalovits, Bell Baker, Timothy Wai, Guy A Rutter, Tristan A Rodriguez, Aida Martinez-Sanchez

Ketone bodies mitigate against systemic inflammation-induced changes in brain energy metabolism and delirium-like deficits in aged mice.

Pub Date : 2026-02-01 DOI: 10.64898/2026.01.22.701114 Pierre-Louis Hollier, M K Kirsten Chui, Javier Cuitavi, Paul Denver, Hugh J Delaney, John C Newman, Colm Cunningham

TLR7 inhibition limits cardiac ischemic injury by disrupting ITGAM-dependent immune-endothelial interaction.

Pub Date : 2026-02-01 DOI: 10.64898/2026.01.17.698774 Yijia Li, Yang Yang, Chanhee Park, Boyang Ren, Ruoxing Li, Amol Shetty, Brittney Williams, Ziyi Li, Lin Zou, Wei Chao

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