Antisense & nucleic acid drug development

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.

Pub Date : 2003-04-01 DOI: 10.1089/108729003321629638 Jens Harborth, Sayda M Elbashir, Kim Vandenburgh, Heiko Manninga, Stephen A Scaringe, Klaus Weber, Thomas Tuschl

Rapid identification of antisense mRNA-expressing clones using strand-specific RT-PCR.

Pub Date : 2003-04-01 DOI: 10.1089/108729003321629656 Michele Cummings, Claire McGurk, John R Masters

Analysis of a mitochondrial apoptotic pathway using Bid-targeted ribozymes in human MCF7 cells in the absence of a caspase-3-dependent pathway.

Pub Date : 2003-04-01 DOI: 10.1089/108729003321629629 Reiko Onuki, Hiroaki Kawasaki, Tadashi Baba, Kazunari Taira