Biochimica et biophysica acta. Molecular basis of disease

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Hypoxic stress promotes astrocyte infiltration-like growth via HIF-1α/GDNF/LOXL2 axis.

Pub Date : 2025-01-31 DOI: 10.1016/j.bbadis.2025.167702 Zimu Li, Shun Xi, Ziqi Zhang, Xugang Kan, Yang Zhang, Miaomiao Wang, Yudong Wang, Yefeng Shi, Haoyue Xu, Baole Zhang

Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart.

Pub Date : 2025-01-31 DOI: 10.1016/j.bbadis.2025.167703 Prachi Umbarkar, Sultan Tousif, Ashish Jaiswal, Arvind Singh Bhati, Angelica Toro Cora, Rohan Sethi, Qinkun Zhang, Hind Lal

Amylin is incorporated into extracellular vesicles in an ESCRT-dependent manner and regulates senescence.

Pub Date : 2025-01-30 DOI: 10.1016/j.bbadis.2025.167699 S Iglesias-Fortes, A C Lockwood, C González-Blanco, D Lozano, A García-Aguilar, O Palomino, G García, M Benito, C Guillén

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