Cell metabolism

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Acetate enables metabolic fitness and cognitive performance during sleep disruption.

Pub Date : 2024-09-03 DOI: 10.1016/j.cmet.2024.07.019 Qinqin He, Liwei Ji, Yanyan Wang, Yarong Zhang, Haiyan Wang, Junyan Wang, Qing Zhu, Maodi Xie, Wei Ou, Jun Liu, Kuo Tang, Kening Lu, Qingmei Liu, Jian Zhou, Rui Zhao, Xintian Cai, Nanfang Li, Yang Cao, Tao Li

TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response.

Pub Date : 2024-09-03 DOI: 10.1016/j.cmet.2024.06.008 Mengqi Zheng, Yunjiao Zhai, Yanbo Yu, Jing Shen, Shuzheng Chu, Enrico Focaccia, Wenyu Tian, Sui Wang, Xuesong Liu, Xi Yuan, Yue Wang, Lixiang Li, Bingcheng Feng, Zhen Li, Xiaohuan Guo, Ju Qiu, Cuijuan Zhang, Jiajie Hou, Yiyuan Sun, Xiaoyun Yang, Xiuli Zuo, Mathias Heikenwalder, Yanqing Li, Detian Yuan, Shiyang Li

Physical exercise mediates cortical synaptic protein lactylation to improve stress resilience.

Pub Date : 2024-09-03 DOI: 10.1016/j.cmet.2024.07.018 Lan Yan, Yajie Wang, Haidong Hu, Diran Yang, Wenjing Wang, Zhihua Luo, Yangze Wang, Fengzhen Yang, Kwok-Fai So, Li Zhang

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