Effects of helical centerline stent vs. straight stent placement on blood flow velocity.

Frontiers in Medical Technology Pub Date : 2023-06-02 eCollection Date: 2023-01-01 DOI:10.3389/fmedt.2023.1196125
Yutaro Kohata, Makoto Ohta, Kazuyoshi Jin, Hitomi Anzai
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Abstract

As an approach to maintain patency in femoropopliteal stenting, a helical stent configuration was proposed, which showed improved patency in clinical trials. However, the effects of helical stent placement on the flow have not been quantitatively analyzed. The purpose of this study was to estimate flow velocities to quantify the influence of helical stent placement. Helical and straight stents were implanted in three healthy pigs, and the flow velocities were estimated using the time-intensity curve (TIC) in the angiography images. The angiographic images indicated thinning of the leading edge of the contrast medium through the helically deformed artery, which was not observed in the straight stent. The slower rise of the TIC peak in the helical stent indicated faster travel of this thinner edge. Arterial expansion due to stenting was observed in all cases, and the expansion rate varied according to location. All cases of helical stent implantation showed that velocity was maintained (55.0%-71.3% velocity retention), unlike for straight stent implantation (43.0%-68.0% velocity retention); however, no significant difference was observed.

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螺旋中心线支架与直支架对血流速度的影响。
作为股动脉支架置入术中保持通畅的一种方法,螺旋支架结构被提出,并在临床试验中显示出更好的通畅性。然而,螺旋支架置入对血流的影响尚未得到定量分析。本研究旨在估算血流速度,以量化螺旋支架置入的影响。在三头健康猪体内植入了螺旋支架和直支架,并利用血管造影图像中的时间-强度曲线(TIC)估算了血流速度。血管造影图像显示,造影剂通过螺旋变形动脉的前缘变薄,而在直支架中却观察不到这种现象。螺旋支架中 TIC 峰值的上升速度较慢,表明这种较薄边缘的移动速度较快。在所有病例中都观察到了支架植入导致的动脉扩张,扩张速度因位置而异。所有植入螺旋支架的病例都显示速度得以保持(速度保持率为 55.0%-71.3% ),而植入直线支架的病例则不同(速度保持率为 43.0%-68.0% );不过,没有观察到显著差异。
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