[Knee range of motion as a marker of the effectiveness of medical intervention in multiple sclerosis].

S A Ryabov, A N Boyko
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Abstract

Objective: To measure the knee range of motion (ROM) in the sagittal plane by video analysis in patients with multiple sclerosis (MS) after a course of medical rehabilitation and determine the minimal clinically important differences (MCID).

Material and methods: We examined 45 patients (37 women, 8 men) with relapsing-remitting (n=38) and secondary-progressive MS before and after a course of medical rehabilitation. Gait parameters were recorded on video analysis system Physiomed Smart («Physiomed», Germany, the Davis protocol).

Results: The course of complex medical rehabilitation contributes to an increase knee ROM in MS patients in a wide range of disability (EDSS <6.5 points). MCID is estimated as 7.14° in mild (EDSS ≤4.0) and as 7.67° in moderate (EDSS=4.5-5.5) gait impairment.

Conclusion: The results will assist clinicians and researchers in interpreting the significance of observed kinematic changes in the knee joint in MS patients after medical intervention.

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[膝关节活动度作为多发性硬化症医学干预有效性的标志]。
目的:通过视频分析测量多发性硬化症(MS)患者经过一个医学康复疗程后的膝关节矢状面活动度(ROM),确定最小临床重要差异(MCID)。材料和方法:我们检查了45例复发缓解型(n=38)和继发性进展性MS患者(37名女性,8名男性)在一个医学康复疗程前后。步态参数记录在视频分析系统Physiomed Smart(«Physiomed»,德国,戴维斯协议)上。结论:本研究结果将有助于临床医生和研究人员解释医学干预后MS患者膝关节运动变化的意义。
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Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Medicine-Psychiatry and Mental Health
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