[The use of clinical molecular and genetic tests in forensic medical opinions].

Rafał Skowronek
{"title":"[The use of clinical molecular and genetic tests in forensic medical opinions].","authors":"Rafał Skowronek","doi":"10.4467/16891716AMSIK.22.005.16234","DOIUrl":null,"url":null,"abstract":"<p><p>Modern molecular biology and clinical genetics have the ability to diagnose many diseases, the presence or absence of which is important in various areas of forensic medical opinion. The aim of the study is to present examples of possible non-standard application of clinical molecular-genetic tests in forensic medicine. From among all the opinions prepared so far at the Department of Forensic Medicine in Katowice, three were selected two of which concerned post-autopsy conclusions relating to the cause of death, and in one case - opinion based on the files of a case related to the suspicion of a maltreated child syndrome in an infant. In all these cases, the results of the molecular and genetic tests were negative, which was taken into account by the experts when formulating the final conclusions of the opinion. The use of clinical molecular and genetic tests in forensic medicine is possible and always brings important additional information that broadens the possibilities of opinion-making and facilitates diagnosis. The areas in which this type of research may be particularly useful are: diagnostics of the basis of thromboembolic complications, modern integrated morphological and molecular diagnostics of neoplasms and diagnostics of genetic defects of connective tissue in children suspected of having abused child syndrome.</p>","PeriodicalId":35709,"journal":{"name":"Archiwum Medycyny Sadowej i Kryminologii","volume":"72 1","pages":"47-52"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archiwum Medycyny Sadowej i Kryminologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4467/16891716AMSIK.22.005.16234","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Modern molecular biology and clinical genetics have the ability to diagnose many diseases, the presence or absence of which is important in various areas of forensic medical opinion. The aim of the study is to present examples of possible non-standard application of clinical molecular-genetic tests in forensic medicine. From among all the opinions prepared so far at the Department of Forensic Medicine in Katowice, three were selected two of which concerned post-autopsy conclusions relating to the cause of death, and in one case - opinion based on the files of a case related to the suspicion of a maltreated child syndrome in an infant. In all these cases, the results of the molecular and genetic tests were negative, which was taken into account by the experts when formulating the final conclusions of the opinion. The use of clinical molecular and genetic tests in forensic medicine is possible and always brings important additional information that broadens the possibilities of opinion-making and facilitates diagnosis. The areas in which this type of research may be particularly useful are: diagnostics of the basis of thromboembolic complications, modern integrated morphological and molecular diagnostics of neoplasms and diagnostics of genetic defects of connective tissue in children suspected of having abused child syndrome.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[在法医意见中使用临床分子和基因测试]。
现代分子生物学和临床遗传学有能力诊断许多疾病,这些疾病的存在与否在法医意见的各个领域都很重要。该研究的目的是提出在法医学中可能的非标准应用临床分子基因测试的例子。在卡托维兹法医司迄今编写的所有意见中,选出了三份意见,其中两份涉及与死因有关的尸检后结论,还有一份意见是根据与怀疑一名婴儿患有受虐待儿童综合症有关的案件档案提出的意见。在所有这些案件中,分子和基因检测的结果都是阴性的,专家们在制定意见的最后结论时考虑到了这一点。在法医中使用临床分子和基因测试是可能的,并且总是带来重要的额外信息,从而扩大了发表意见的可能性并促进了诊断。这类研究可能特别有用的领域是:血栓栓塞并发症的基础诊断,肿瘤的现代综合形态学和分子诊断,以及怀疑患有虐待儿童综合症的儿童结缔组织遗传缺陷的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
0.60
自引率
0.00%
发文量
12
审稿时长
12 weeks
期刊介绍: Archiwum Medycyny Sądowej i Kryminologii przyjmuje w języku polskim: prace doświadczalne, poglądowe, kazuistyczne, artykuły o charakterze szkoleniowym z medycyny sądowej, kryminologii i dziedzin pokrewnych, opracowania z zakresu etyki i deontologii lekarskiej, streszczenia prac obcych, oceny książek, sprawozdania z działalności PTMSiK, sprawozdania ze zjazdów krajowych i zagranicznych, komunikaty Zarządu Głównego PTMSiK, listy do Redakcji. Autor powinien podać, do jakiej kategorii zalicza tekst nadesłanej pracy. Przyjmowane do druku będą również prace autorów zagranicznych w języku angielskim.
期刊最新文献
Supplement to the work „Smoothbore hunting ammunition – a historical overview” Pro Memoria: Prof. Roman Mądro (1943-2023) Pro Memoria: prof. Jerzy Jan Janica (1939-2022) Review of the experiences of users of methaqualone and methaqualone derivatives. An analysis of online forums. COVID-19-related excess mortality - an overview of the current evidence.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1