Clinical profile and outcomes of primary percutaneous coronary intervention in young patients

Ivan Petry Feijó, Márcia Moura Schmidt, Renato Budzyn David, João Maximiliano Pedron Martins, Karine Elisa Schmidt, Carlos Antonio Mascia Gottschall, Alexandre Schaan de Quadros
{"title":"Clinical profile and outcomes of primary percutaneous coronary intervention in young patients","authors":"Ivan Petry Feijó,&nbsp;Márcia Moura Schmidt,&nbsp;Renato Budzyn David,&nbsp;João Maximiliano Pedron Martins,&nbsp;Karine Elisa Schmidt,&nbsp;Carlos Antonio Mascia Gottschall,&nbsp;Alexandre Schaan de Quadros","doi":"10.1016/j.rbciev.2015.01.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>The epidemiology of acute myocardial infarction with ST-segment elevation (STEMI) has been modified in recent years, focusing on young people. Our goal was compare the clinical profile, laboratory, angiographic, and 30-day clinical outcomes of patients ≤ 40 years with those &gt; 40 years undergoing primary percutaneous coronary intervention (pPCI).</p></div><div><h3>Methods</h3><p>Prospective cohort study of consecutive patients undergoing pPCI between 2009 and 2011.</p></div><div><h3>Results</h3><p>A total of 1,055 patients were included, 3.3% of them ≤ 40 years. Young patients were more often black, smokers and with a family history of coronary artery disease, and less often hypertensive and dyslipidemic. In patients ≤ 40 years, leukocyte count and ultrasensitive troponin levels at admission were higher, and high density lipoprotein-cholesterol, lower. The left anterior descending artery as a culprit vessel and left ventricular ejection fraction did not differ between groups. Although the TIMI 3 flow pre-intervention was similar, young people showed higher prevalence of myocardial blush 3 pre-procedure. The door-to-balloon time was lower in younger patients (1.0 hour [0.8-1.4 hour] vs. 1.3 hour [0.9-1.7 hour]; <em>p</em> = 0.03). At 30 days, patients ≤ 40 years had a mortality of 0% vs. 8.8% for patients &gt; 40 years (<em>p</em> = 0.07).</p></div><div><h3>Conclusions</h3><p>Patients ≤ 40 years with STEMI and undergoing pPCI show differences in clinical, angiographic and procedural characteristics compared to those &gt; 40 years. In this analysis, representative of the current medical practice, the 30-day mortality of these patients was very low.</p></div>","PeriodicalId":101094,"journal":{"name":"Revista Brasileira de Cardiologia Invasiva (English Edition)","volume":"23 1","pages":"Pages 48-51"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbciev.2015.01.007","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Brasileira de Cardiologia Invasiva (English Edition)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214123515000113","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8

Abstract

Background

The epidemiology of acute myocardial infarction with ST-segment elevation (STEMI) has been modified in recent years, focusing on young people. Our goal was compare the clinical profile, laboratory, angiographic, and 30-day clinical outcomes of patients ≤ 40 years with those > 40 years undergoing primary percutaneous coronary intervention (pPCI).

Methods

Prospective cohort study of consecutive patients undergoing pPCI between 2009 and 2011.

Results

A total of 1,055 patients were included, 3.3% of them ≤ 40 years. Young patients were more often black, smokers and with a family history of coronary artery disease, and less often hypertensive and dyslipidemic. In patients ≤ 40 years, leukocyte count and ultrasensitive troponin levels at admission were higher, and high density lipoprotein-cholesterol, lower. The left anterior descending artery as a culprit vessel and left ventricular ejection fraction did not differ between groups. Although the TIMI 3 flow pre-intervention was similar, young people showed higher prevalence of myocardial blush 3 pre-procedure. The door-to-balloon time was lower in younger patients (1.0 hour [0.8-1.4 hour] vs. 1.3 hour [0.9-1.7 hour]; p = 0.03). At 30 days, patients ≤ 40 years had a mortality of 0% vs. 8.8% for patients > 40 years (p = 0.07).

Conclusions

Patients ≤ 40 years with STEMI and undergoing pPCI show differences in clinical, angiographic and procedural characteristics compared to those > 40 years. In this analysis, representative of the current medical practice, the 30-day mortality of these patients was very low.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
初级经皮冠状动脉介入治疗的临床特点和结果
背景急性心肌梗死st段抬高(STEMI)的流行病学近年来有所改变,主要集中在年轻人。我们的目标是比较≤40岁患者的临床资料、实验室、血管造影和30天临床结果。接受原发性经皮冠状动脉介入治疗(pPCI) 40年。方法对2009 - 2011年间连续接受pPCI的患者进行前瞻性队列研究。结果共纳入1055例患者,年龄≤40岁的占3.3%。年轻患者多为黑人、吸烟者和有冠状动脉疾病家族史的人,高血压和血脂异常的人较少。在≤40岁的患者中,入院时白细胞计数和超敏肌钙蛋白水平较高,高密度脂蛋白-胆固醇水平较低。左前降支为主犯血管,左心室射血分数组间无差异。虽然timi3血流预干预相似,但年轻人在术前心肌脸红的发生率更高。年轻患者到球囊的时间较短(1.0小时[0.8-1.4小时]vs. 1.3小时[0.9-1.7小时];P = 0.03)。30天时,≤40岁的患者死亡率为0%,而≤40岁的患者死亡率为8.8%;40年(p = 0.07)。结论≤40年的STEMI患者与接受pPCI的患者相比,在临床、血管造影和手术特征上存在差异;40年。在本分析中,代表了目前的医疗实践,这些患者的30天死亡率非常低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Primary or rescue percutaneous coronary intervention in smokers Right heart catheterization through ultrasound-guided antecubital vein approach Transition between ticagrelor and two different doses of clopidogrel at hospital discharge in patients with acute coronary syndrome submitted to percutaneous coronary intervention Rare form of coronary fistula draining into the right ventricular apex Evaluation of scattered radiation and impact of local protective devices in an interventional cardiology laboratory
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1