Comparing the Diagnostic Value of Four Dementia Tests in the Amnestic and Healthy Elderly.

IF 1 Q4 NEUROSCIENCES Basic and Clinical Neuroscience Pub Date : 2023-01-01 DOI:10.32598/bcn.2022.1745.1
Fatemah Khamseh, Gholamreza Hadjati, Hossein Nahvinejad, Zahra Nouparast, Masomeh Salehi, Maryam Noroozian, Mahshid Foroughan, Farshid Alaedini, Afrooz Saffarifard, Faraneh Farin, Mehrdad Khansari, Maryam Pourseid Mohammad, Zahra Ahmadi
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Abstract

Introduction: This study aimed to compare the diagnostic value of four questionnaires for the diagnosis of neurocognitive disorders (NCDs) in the elderly.

Methods: In this project, people older than 60 years who lived in Tehran were investigated. A total of 99 literate cases were enrolled in the study, and four questionnaires, including functional assessment staging tool (FAST), abbreviated mental test score (AMTS), mini-mental state examination (MMSE), and modified Persian test of elderly for assessment of cognition and executive function (PEACE) were completed for them. They were then referred to a neuropsychiatrist, and the status of their cognition and neurobehavior was determined. The specialists were blinded to the results of the tests.

Results: Of the 99 participants studied, 39 cases were healthy, eight cases had mild Alzheimer's disease, 38 had amnesic MCI, five cases had secondary dementia, and nine cases had mixed vascular dementia and Alzheimer's disease. The area under the ROC curve for distinguishing the healthy group from the rest of the population was 0.692, 0.629, 0.734, and 0.751 for the FAST, AMTS, MMSE, and NBCSS questionnaires, respectively.

Conclusion: MMSE and NBCSS tests had better diagnostic power than the other two tests to distinguish the healthy group from the rest of the population.

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四种痴呆测试对老年人和健康老年人的诊断价值比较。
引言:本研究旨在比较四份问卷对老年人神经认知障碍(NCDs)诊断的诊断价值。方法:在该项目中,对居住在德黑兰的60岁以上的人进行了调查。本研究共招募了99名识字病例,并为他们完成了四份问卷,包括功能评估分期工具(FAST)、简略心理测试分数(AMTS)、迷你心理状态检查(MMSE)和老年人认知和执行功能评估改良波斯测试(PEACE)。然后,他们被转介给神经精神科医生,并确定他们的认知和神经行为状态。专家们对测试结果视而不见。结果:在研究的99名参与者中,39例健康,8例患有轻度阿尔茨海默病,38例患有遗忘性MCI,5例患有继发性痴呆,9例患有血管性痴呆和阿尔茨海默病。FAST、AMTS、MMSE和NBCSS问卷的ROC曲线下区分健康组和其他人群的面积分别为0.692、0.629、0.734和0.751。结论:MMSE和NBCSS测试比其他两种测试具有更好的诊断能力,可以区分健康组和其他人群。
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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
64
审稿时长
4 weeks
期刊介绍: BCN is an international multidisciplinary journal that publishes editorials, original full-length research articles, short communications, reviews, methodological papers, commentaries, perspectives and “news and reports” in the broad fields of developmental, molecular, cellular, system, computational, behavioral, cognitive, and clinical neuroscience. No area in the neural related sciences is excluded from consideration, although priority is given to studies that provide applied insights into the functioning of the nervous system. BCN aims to advance our understanding of organization and function of the nervous system in health and disease, thereby improving the diagnosis and treatment of neural-related disorders. Manuscripts submitted to BCN should describe novel results generated by experiments that were guided by clearly defined aims or hypotheses. BCN aims to provide serious ties in interdisciplinary communication, accessibility to a broad readership inside Iran and the region and also in all other international academic sites, effective peer review process, and independence from all possible non-scientific interests. BCN also tries to empower national, regional and international collaborative networks in the field of neuroscience in Iran, Middle East, Central Asia and North Africa and to be the voice of the Iranian and regional neuroscience community in the world of neuroscientists. In this way, the journal encourages submission of editorials, review papers, commentaries, methodological notes and perspectives that address this scope.
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