New approaches in childhood asthma treatment.

IF 3 4区医学 Q2 ALLERGY Current Opinion in Allergy and Clinical Immunology Pub Date : 2023-08-01 DOI:10.1097/ACI.0000000000000922

Riccardo Castagnoli, Ilaria Brambilla, Mattia Giovannini, Gian Luigi Marseglia, Amelia Licari

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Abstract

Purpose of review: This review aims to summarize the most recent advances in asthma management, focusing on novel approaches to pediatric asthma.

Recent findings: In recent years, the therapeutic tools for pediatric asthma have expanded significantly for both the nonsevere and severe forms. The use of anti-inflammatory treatment, even for the mildest cases, and the withdrawal of symptomatic bronchodilation as monotherapy have been included in the most recent guidelines. Also, different biological therapies have revolutionized the therapeutical approach for severe uncontrolled asthma in children and adolescents.

Summary: With the expanding landscape of novel therapeutic approaches for pediatric asthma, further evidence is needed to help clinicians choose the best option for patients, particularly those with severe asthma. The identification of novel predictive biomarkers may also help pediatricians in selecting children and adolescents for innovative therapies.

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儿童哮喘治疗新途径

综述目的:本综述旨在总结哮喘管理的最新进展，重点是儿科哮喘的新方法。最近的发现:近年来，儿童哮喘的治疗工具在非严重和严重形式上都有显著的扩展。使用抗炎治疗，即使是最轻微的病例，以及停止有症状的支气管扩张作为单一疗法已列入最新的指南。此外，不同的生物疗法已经彻底改变了儿童和青少年严重不受控制的哮喘的治疗方法。摘要:随着儿科哮喘新治疗方法的不断扩大，需要进一步的证据来帮助临床医生为患者选择最佳选择，特别是那些严重哮喘患者。新的预测性生物标志物的鉴定也可以帮助儿科医生选择儿童和青少年进行创新治疗。

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来源期刊

Current Opinion in Allergy and Clinical Immunology 医学-过敏

CiteScore

5.90

自引率

3.60%

发文量

109

审稿时长

6-12 weeks

期刊介绍： This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on one to three topics, every issue of Current Opinion in Allergy and Clinical Immunology delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as upper airway disease; mechanisms of allergy and adult asthma; paediatric asthma and development of atopy; food and drug allergies; and immunotherapy.

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