Continuation of Geriatric Discharge Medication in Primary Care and its Association with Rehospitalizations - A Cohort Study.

IF 1.5 4区 医学 Q4 CHEMISTRY, MEDICINAL Pharmazie Pub Date : 2023-08-01 DOI:10.1691/ph.2023.3558
M Freitag, T Bülow, S Fleig, A Eisert, O Krause, L C Bollheimer, T Laurentius
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Abstract

Transition of care in geriatric patients is a complex and high risk process, particularly the continuation of discharge medication in primary care. We aimed to determine how general practitioners' management of geriatric patients' discharge medication is associated with rehospitalizations. A prospective monocentric cohort study was done in an acute geriatric inpatient clinic with six-months follow-up. Acutely hospitalized patients ≥ 70 years old with functional impairment and frailty currently taking medications were followed up after hospital discharge and continuation (n=27) or change (n=44) of discharge medication by the General Practitioner was determined. Outcomes were rehospitalizations, days spent at home and time until recurrent rehospitalizations. 71 patients (mean age 82 years, 46 women [65%]) were followed up for six months after hospital discharge. In a negative binomial regression model, the rehospitalization rate after three months was 3.8 times higher in participants whose discharge medication was changed (p = 0.023). The effect did not persist over six months. Patients who were continued on their discharge medication were rehospitalized significantly later and/or less often during the six months observation period, statistically measured by a recurrent events survival model (HR 0.267, p = 0.003). In conclusion, continuation of discharge medication after an acute hospitalization in a specialized geriatric clinic could prevent early rehospitalizations.

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初级保健中老年人出院用药的延续及其与再住院的关系——一项队列研究。
老年患者的护理过渡是一个复杂和高风险的过程,特别是在初级保健中继续进行出院药物治疗。我们的目的是确定全科医生对老年患者出院用药的管理与再住院的关系。一项前瞻性单中心队列研究在急性老年住院患者门诊进行了6个月的随访。≥70岁的急性住院患者,伴有功能障碍和虚弱,目前正在服药,出院后随访,确定全科医生继续(n=27)或改变(n=44)出院用药。结果是再住院、在家的天数和复发再住院的时间。71例患者出院后随访6个月,平均年龄82岁,女性46例(65%)。在负二项回归模型中,改变出院药物的受试者3个月后再住院率高出3.8倍(p = 0.023)。这种效果并没有持续超过6个月。在6个月的观察期内,继续服用出院药物的患者再次住院的时间明显推迟,而且/或更少,用复发事件生存模型进行统计学测量(HR 0.267, p = 0.003)。综上所述,在老年专科诊所急性住院后继续出院用药可以预防早期再住院。
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来源期刊
Pharmazie
Pharmazie 医学-化学综合
CiteScore
3.10
自引率
0.00%
发文量
56
审稿时长
1.2 months
期刊介绍: The journal DiePharmazie publishs reviews, experimental studies, letters to the editor, as well as book reviews. The following fields of pharmacy are covered: Pharmaceutical and medicinal chemistry; Pharmaceutical analysis and drug control; Pharmaceutical technolgy; Biopharmacy (biopharmaceutics, pharmacokinetics, biotransformation); Experimental and clinical pharmacology; Pharmaceutical biology (pharmacognosy); Clinical pharmacy; History of pharmacy.
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