{"title":"Total artificial heart system.","authors":"Michael Essandoh, Nicolas Kumar","doi":"10.1097/AIA.0000000000000377","DOIUrl":null,"url":null,"abstract":"Heart failure is a ubiquitous condition affecting over 60 million people globally and causes substantial morbidity and mortality. Conventionally, terminal heart failure is treated with guidelinedirected medical therapy and cardiac resynchronization therapy, which unfortunately becomes refractory over time, and necessitates escalation to advanced therapies or heart transplantation. Heart transplantation is the ultimate therapy for medically refractory advanced heart failure. Still, the limited supply of donor hearts (~4000 yearly) has spurred the development of mechanical circulatory support (MCS) strategies for heart failure treatment as bridge-to-decision making, bridge-to-myocardial recovery, bridge-to-orthotopic heart transplantation (BTT), and destination therapy (DT).","PeriodicalId":46852,"journal":{"name":"INTERNATIONAL ANESTHESIOLOGY CLINICS","volume":"60 4","pages":"39-45"},"PeriodicalIF":0.8000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"INTERNATIONAL ANESTHESIOLOGY CLINICS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/AIA.0000000000000377","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Heart failure is a ubiquitous condition affecting over 60 million people globally and causes substantial morbidity and mortality. Conventionally, terminal heart failure is treated with guidelinedirected medical therapy and cardiac resynchronization therapy, which unfortunately becomes refractory over time, and necessitates escalation to advanced therapies or heart transplantation. Heart transplantation is the ultimate therapy for medically refractory advanced heart failure. Still, the limited supply of donor hearts (~4000 yearly) has spurred the development of mechanical circulatory support (MCS) strategies for heart failure treatment as bridge-to-decision making, bridge-to-myocardial recovery, bridge-to-orthotopic heart transplantation (BTT), and destination therapy (DT).
期刊介绍：
International Anesthesiology Clinics is a valuable resource for any medical professional seeking to stay informed and up-to-date regarding developments in this dynamic specialty. Each hardbound issue of this quarterly publication presents a comprehensive review of a single topic in a new or changing area of anesthesiology. The timely, tightly focused review articles found in this publication give anesthesiologists the opportunity to benefit from the knowledge of leading experts in this rapidly changing field.
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