Percutaneous Transhepatic Radiologic Intervention of Biliary Complications following Liver Transplantation: A Single-center Experience.

IF 0.3 Q4 TRANSPLANTATION International Journal of Organ Transplantation Medicine Pub Date : 2022-01-01
A Rasekhi, Z Gholami, M Azizi, S A Malek-Hosseini, H Salahi
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Abstract

Background: Biliary complications are the leading cause of morbidity and mortality in patients undergo¬ing Liver Transplantation (LT). Post-biliary transplantation strictures (BSs) are a severe problem with a high risk of graft failure. However, management of these BSs has remained controversial, and consid¬erable variability has been reported in Percutaneous Transhepatic Radiological Interventions (PTRIs) related to broad differences in technical procedures.

Objective: This study aimed to evaluate the efficacy of percutaneous treatments in managing post-LT BSs in a center in Shiraz.

Methods: PTRIs including balloon dilatation, metallic stent, and internal or internal-external hand-made plastic stent insertion were done for 34 transplanted patients with BSs referring to the Interventional Radiology Unit of Shiraz Namazi Hospital. Technical success rate, patency rates, and complications were evaluated.

Results: The. In this study, 31 strictures were successfully treated without any significant difference between the anastomotic and non-anastomotic types of stricture (success rate: 91.2%). Based on the results, 12- , 24-, and 36-month primary patency rates were 90.1%, 84.5%, and 76.8%, respectively. The secondary patency rate was 100% at 12 and 24 months and 93.3% at 36 and 60 months. The rate of minor complica¬tions (mild cholangitis and hemobilia) was 6.4%, and no major complications were detected.

Conclusion: According to the findings, PTRI is an effective method for treating anastomotic and non-anas- tomotic strictures with a high success rate and low complications.

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肝移植术后胆道并发症的经皮经肝放射干预:单中心经验。
背景:胆道并发症是肝移植(LT)患者发病和死亡的主要原因。胆道移植后狭窄(BSs)是一个严重的问题,具有很高的移植失败风险。然而,这些BSs的管理仍然存在争议,并且在经皮经肝放射干预(PTRIs)中有相当大的差异,这与技术程序的广泛差异有关。目的:本研究旨在评估经皮治疗在设拉子中心治疗lt后BSs的疗效。方法:对设拉子纳马兹医院介入放射科收治的34例BSs移植患者行球囊扩张、金属支架、内置或内外置手工制作塑料支架等PTRIs治疗。评估技术成功率、通畅率和并发症。结果:。本研究成功治疗31例狭窄,吻合型和非吻合型狭窄无明显差异(成功率:91.2%)。结果显示,12、24、36个月原发性通畅率分别为90.1%、84.5%、76.8%。12、24个月的二次通畅率为100%,36、60个月的二次通畅率为93.3%。轻微并发症(轻度胆管炎、胆道出血)发生率为6.4%,无重大并发症发生。结论:PTRI是一种治疗吻合口及非吻合口狭窄的有效方法,成功率高,并发症少。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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