A Rare Case of Ectopic Adrenocorticotropic Hormone Secretion from Pancreatic Neuroendocrine Tumour Presenting with Cushing Syndrome.

IF 1 Q4 GASTROENTEROLOGY & HEPATOLOGY GE Portuguese Journal of Gastroenterology Pub Date : 2023-06-01 DOI:10.1159/000521518
Soon Liang Lee, Chiun Yann Ng, Jasminder Sidhu, Asmawiza Awang
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Abstract

Ectopic adrenocorticotropic hormone secretion (EAS) from the pancreatic neuroendocrine tumour (PNET) is rare, aggressive, and challenging to treat. We hereby present a rare case of EAS from PNET presenting with Cushing syndrome diagnosed with endoscopic ultrasound-guided fine-needle aspiration cytology. This case highlights the advanced presentation of EAS from PNET with poor clinical correlation of hypercortisolism and the grade of PNET.

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以库欣综合征为表现的胰腺神经内分泌肿瘤异位促肾上腺皮质激素分泌一例。
胰腺神经内分泌肿瘤(PNET)的异位促肾上腺皮质激素分泌(EAS)是罕见的,侵袭性的,并且具有挑战性的治疗。我们在此报告一例罕见的来自PNET的EAS,以超声内镜引导下的细针穿刺细胞学诊断为库欣综合征。本病例强调了PNET的晚期EAS表现,高皮质醇血症与PNET分级的临床相关性较差。
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来源期刊
GE Portuguese Journal of Gastroenterology
GE Portuguese Journal of Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
1.60
自引率
11.10%
发文量
62
审稿时长
21 weeks
期刊介绍: The ''GE Portuguese Journal of Gastroenterology'' (formerly Jornal Português de Gastrenterologia), founded in 1994, is the official publication of Sociedade Portuguesa de Gastrenterologia (Portuguese Society of Gastroenterology), Sociedade Portuguesa de Endoscopia Digestiva (Portuguese Society of Digestive Endoscopy) and Associação Portuguesa para o Estudo do Fígado (Portuguese Association for the Study of the Liver). The journal publishes clinical and basic research articles on Gastroenterology, Digestive Endoscopy, Hepatology and related topics. Review articles, clinical case studies, images, letters to the editor and other articles such as recommendations or papers on gastroenterology clinical practice are also considered. Only articles written in English are accepted.
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