Hand, Foot, and Mouth Disease Outbreak What You Need to Know.

Q3 Pharmacology, Toxicology and Pharmaceutics Infectious disorders drug targets Pub Date : 2023-01-01 DOI:10.2174/1871526523666230601121101
Amandeep Singh, Okesanya Olalekan John, Bello Barakat Bisola
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Abstract

HFMD is an obvious disease in children mostly below the age of five constituting a public health challenge to Asian-Pacific and developing countries majorly. This disease is often caused by enterovirus 71 (EV71) and Coxsackievirus A16. HFMD is a mild degree fever and general illness which manifests for about 10 days. Young age, male gender, poor hygiene, and high social contacts are some risk factors. HFMD can be diagnosed clinically by isolating the virus from stool and pharynx and identifying it on Light microscopic examination. Polymerase Chain Reaction Assay is a gold standard for confirming the virus from swabbed lesions. Late confirmation could lead to severe complications. There are no specific treatments and vaccines licensed for general use in the treatment of various serotypes of HFMD. The major strategy to prevent and control this disease is to strictly follow the WHO 8 guidelines to curb the spread of the disease.

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手足口病爆发你需要知道的
手足口病是一种常见于5岁以下儿童的明显疾病,主要对亚太地区和发展中国家构成公共卫生挑战。该病通常由肠病毒71型(EV71)和柯萨奇病毒A16引起。手足口病是一种轻度发烧和一般疾病,症状约为10天。年轻、男性、卫生条件差和社会交往频繁是一些危险因素。手足口病可通过从粪便和咽中分离病毒,并在光镜检查下识别。聚合酶链反应试验是从拭子病变中确认病毒的金标准。晚确认可能导致严重的并发症。目前还没有专门的治疗方法和疫苗被许可用于治疗各种血清型手足口病。预防和控制这种疾病的主要战略是严格遵守世卫组织8项指导方针,以遏制疾病的传播。
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来源期刊
Infectious disorders drug targets
Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
3.10
自引率
0.00%
发文量
123
期刊介绍: Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.
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