Particulate Gastric Contents in Patients Prescribed Glucagon-Like Peptide 1 Receptor Agonists After Appropriate Perioperative Fasting: A Report of 2 Cases.

IF 0.5 A&A Practice Pub Date : 2023-08-01 DOI:10.1213/XAA.0000000000001712
Phillip Ryan Wilson, Kathryn H Bridges, Sylvia H Wilson
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Abstract

Glucagon-like peptide 1 (GLP-1) receptor agonists have surged in popularity for the treatment of both diabetes mellitus and obesity. While GLP-1 reduces proximal gastrointestinal motility and delays gastric emptying, the impact of these medications on adequate fasting before surgery is not clear. We present 2 cases of particulate gastric contents after following appropriate presurgical fasting in diabetic patients taking GLP-1 receptor agonists and review current literature regarding perioperative implications of these drugs.

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服用胰高血糖素样肽1受体激动剂患者围手术期适当禁食后胃内容物颗粒化:附2例报告
胰高血糖素样肽1 (GLP-1)受体激动剂在治疗糖尿病和肥胖方面的应用越来越广泛。虽然GLP-1可减少近端胃肠运动并延迟胃排空,但这些药物对术前充分禁食的影响尚不清楚。我们报告了2例服用GLP-1受体激动剂的糖尿病患者术前适当禁食后胃内容物颗粒,并回顾了有关这些药物围手术期影响的现有文献。
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A&A Practice
A&A Practice ANESTHESIOLOGY-
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期刊介绍: A & A Case Reports, our new online journal publishing Case Reports, related Editorial Commentary, and Correspondence. Anesthesia & Analgesia 1 and Anesthesiology 2 recently announced that they were suspending publication of Case Reports. One reason is that Case Reports typically reduce the Impact Factor of a journal because they are rarely cited. Regardless of the merits of Impact Factor as a metric of journal worth, journals and their editors necessarily consider Impact Factor in strategic planning. At the same time, Case Reports are appreciated by readers for describing “real life” management of difficult or unusual cases not often encountered by practitioners. In a recent issue of Anesthesia & Analgesia, Steven Shafer1 identified many Case Reports whose publication launched productive careers dedicated to solving the puzzle posed by an unusual observation in a single patient.
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