Botulinum toxin in the treatment of residual limb hyperhidrosis: A systematic review

Q3 Medicine Rehabilitacion Pub Date : 2023-07-01 DOI:10.1016/j.rh.2022.07.003
J. Rocha Melo , M.A. Rodrigues , M. Caetano , P. Cantista
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引用次数: 0

Abstract

The aim of the study was to analyze the current evidence regarding the effect of intradermal injections of botulinum toxin on residual limb hyperhidrosis. A comprehensive search of the MEDLINE and Scopus databases from inception until December 2021 was performed according to the PRISMA guidelines. The search terms used were “botulinum toxins”, “botulinum toxins, Type A”, “rimabotulinumtoxinB”, “amputees”, “amputation stumps”, “amputation” and “residual limbs”. The specific controlled vocabulary of each database was also used (e.g., MeSH). One hundred and thirty-one different studies met this search criteria and were reviewed. Two independent reviewers assessed the quality of the manuscripts. Eight studies met the inclusion criteria for this review. The results demonstrated an improvement in residual limb hyperhidrosis in all studies. Botulinum toxin A or B can be regarded as safe and effective for the treatment of residual limb hyperhidrosis, as well as improving prosthesis use and quality of life.

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肉毒杆菌毒素治疗残肢多汗症:系统综述
本研究的目的是分析目前关于皮内注射肉毒杆菌毒素对残肢多汗症的影响的证据。根据PRISMA指南,从成立到2021年12月,对MEDLINE和Scopus数据库进行了全面搜索。使用的搜索词是“肉毒杆菌毒素”、“肉毒杆菌素,A型”、“原肉毒杆菌毒素B”、“截肢者”、“截肢残端”、“断肢”和“残肢”。还使用了每个数据库的特定受控词汇(例如MeSH)。一百三十一项不同的研究符合这一搜索标准,并进行了审查。两名独立评审员对手稿的质量进行了评估。八项研究符合本次审查的纳入标准。结果表明,在所有研究中,残肢多汗症都得到了改善。肉毒毒素A或B可以被认为是安全有效的治疗残肢多汗症,以及改善假肢的使用和生活质量。
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来源期刊
Rehabilitacion
Rehabilitacion Medicine-Rehabilitation
CiteScore
0.80
自引率
0.00%
发文量
63
期刊介绍: La revista que es desde hace más de 40 años la publicación oficial de la Sociedad Española de Rehabilitación y referente de la mayoría de las Sociedades de la Especialidad de los países americanos de habla hispana. Se publican 5 números pluritemáticos al año y uno monográfico sobre un tema del mayor interés y actualidad designado por el consejo de redacción.
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