Unique contributions of specific neuropsychiatric symptoms to caregiver burden in informal caregivers family members of patients with dementia.

IF 1.5 4区 医学 Q3 PSYCHIATRY Cognitive Neuropsychiatry Pub Date : 2023-09-01 Epub Date: 2023-09-05 DOI:10.1080/13546805.2023.2255338
Miroslav Hanzevacki, Jelena Lucijanic, Dina Librenjak, Marko Lucijanic, Vesna Juresa
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Abstract

Introduction: We aimed to evaluate how the presence of individual neuropsychiatric symptoms in non-institutionalised patients with dementia is associated with caregiver burden of their informal caregivers, family members.

Methods: We performed a cross-sectional study on a total of 131 pairs of one informal caregiver family member and non-institutionalised patient with dementia in a family medicine practices in a city of Zagreb, Croatia. Caregiver measures included Zarit Burden Interview (ZBI) whereas patient measures included Mini mental state examination (MMSE), Barthel index and Neuropsychiatric Inventory Questionnaire (NPI-Q).

Results: Total NPI-Q score explained 21% of overall burden. In order of strength of the association, after adjustments for age, sex, MMSE and Barthel index, overall burden was significantly associated with higher NPI-Q scores for agitation/aggression, apathy/indifference, irritability/lability, disinhibition, motor disturbance, appetite/eating, depression/dysphoria, anxiety, elation/euphoria and nighttime behaviours. When evaluating mutually independent contribution of unique NPI-Q symptoms to caregiver burden, agitation/aggression and apathy/indifference remained only two mutually independently associated symptoms, each explaining 5% of overall burden in this context.

Conclusions: Informal caregivers who provide for family members with dementia suffering from agitation/aggression or apathy/indifference should be recognised as under special risk for the development of caregiver burden and considered as candidates for early targeted interventions.

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特定神经精神症状对痴呆症患者非正式照顾者家庭成员照顾者负担的独特贡献。
引言:我们旨在评估非住院痴呆患者个体神经精神症状的存在与他们的非正式照顾者、家庭成员的照顾者负担之间的关系。方法:我们对克罗地亚萨格勒布市一家家庭医疗机构的131对非正规护理者家庭成员和非住院痴呆症患者进行了横断面研究。护理人员测量包括Zarit负担访谈(ZBI),而患者测量包括迷你精神状态检查(MMSE)、Barthel指数和神经精神问卷(NPI-Q)。结果:NPI-Q总分解释了21%的总体负担。按照关联强度的顺序,在调整了年龄、性别、MMSE和Barthel指数后,总体负担与较高的NPI-Q分数显著相关,这些分数包括激动/攻击性、冷漠/冷漠、易怒/不稳定、去抑制、运动障碍、食欲/饮食、抑郁/烦躁、焦虑、兴高采烈/欣快和夜间行为。当评估独特的NPI-Q症状对照顾者负担的相互独立贡献时,激动/攻击和冷漠/冷漠仍然是两种相互独立的相关症状,在这种情况下,每种症状都解释了5%的总体负担。结论:为患有焦虑/攻击或冷漠/冷漠的痴呆症家庭成员提供护理的非正式护理人员应被视为护理人员负担发展的特殊风险,并被视为早期有针对性干预的候选者。
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来源期刊
CiteScore
3.20
自引率
11.80%
发文量
18
审稿时长
>12 weeks
期刊介绍: Cognitive Neuropsychiatry (CNP) publishes high quality empirical and theoretical papers in the multi-disciplinary field of cognitive neuropsychiatry. Specifically the journal promotes the study of cognitive processes underlying psychological and behavioural abnormalities, including psychotic symptoms, with and without organic brain disease. Since 1996, CNP has published original papers, short reports, case studies and theoretical and empirical reviews in fields of clinical and cognitive neuropsychiatry, which have a bearing on the understanding of normal cognitive processes. Relevant research from cognitive neuroscience, cognitive neuropsychology and clinical populations will also be considered. There are no page charges and we are able to offer free color printing where color is necessary.
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