Not So Innocent Indapamide.

Shayan Aziz, Satyan Rajbhandari
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Abstract

A 58-year-old asymptomatic man was referred by his general practitioner for abnormal blood results. Routine blood tests to monitor blood count and kidney functions showed neutropenia and hyponatremia. He was euvolemic on examination. A further detailed investigation did not reveal any cause of neutropenia and hyponatremia. After careful assessment of their drug history, it transpired he recently started Indapamide for uncontrolled hypertension. Hyponatraemia is a common side effect of Indapamide and in addition, it can rarely cause agranulocytosis and leukopenia. Indapamide was stopped and the blood counts started to improve and became normal after two weeks.

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不那么无辜的吲达帕胺。
一名58岁无症状男子因血液结果异常由全科医生转诊。血常规检查监测血细胞计数和肾功能显示中性粒细胞减少症和低钠血症。他在考试中表现得很亢奋。进一步的详细调查没有发现中性粒细胞减少症和低钠血症的任何原因。在仔细评估了他们的用药史后,得知他最近开始使用吲达帕胺治疗不受控制的高血压。低钠血症是吲达帕胺常见的副作用,此外,它很少引起粒细胞缺乏症和白细胞减少症。停用吲达帕胺后,血液计数开始改善,两周后恢复正常。
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0.80
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0.00%
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304
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