Hepatitis B, C And Hiv Exposure On Nat And Clia Blood Examination Methods At Regional Blood Centre Abbottabad.

Q3 Medicine Journal of Ayub Medical College, Abbottabad : JAMC Pub Date : 2023-04-01 DOI:10.55519/JAMC-02-11600

Romana Irshad, Umer Farooq, Tahir Shah, Adeel Gul, Amir Badshah

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Abstract

Background: Blood transfusion is a lifesaving method in clinical emergencies. Despite various preventive measures, the spread of Hepatitis B, C and HIV remains a big issue in Pakistan. This study was done to describe transfusion transmitted diseases using NAT and CLIA techniques, on exposure to these viruses.

Methods: This study was conducted from 1st April to 25th August 2022. A descriptive study was done along with univariate analysis. The data was obtained from the regional blood centre in Abbottabad and it consists of reactive and non-reactive cases of NAT and CLIA in the sample size of 6233 donors. Data was collected from donors, and selected according to predefined criteria.

Results: In 6233 samples, 53 were reactive for either Hepatitis B, C or HIV. Forty-seven were reactive with both CLIA and NAT. 6 were reactive with NAT only and 6107 were non-reactive.

Conclusions: NAT yield detected in this study is 0.096%. (1:1039 donations). It implies that NAT should be the preferred method for screening in blood banks.

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阿伯塔巴德地区血液中心的Nat和Clia血液检查方法对乙型、丙型肝炎和艾滋病毒的暴露。

背景:输血是临床急诊救治的重要手段。尽管采取了各种预防措施，乙型肝炎、丙型肝炎和艾滋病毒的传播仍然是巴基斯坦的一个大问题。本研究使用NAT和CLIA技术描述了暴露于这些病毒的输血传播疾病。方法:本研究于2022年4月1日至8月25日进行。描述性研究结合单变量分析。数据来自阿伯塔巴德的区域血液中心，它包括6233名献血者中反应性和非反应性NAT和CLIA病例。从捐助者处收集数据，并根据预先确定的标准进行选择。结果:在6233份样本中，53份对乙型、丙型肝炎或艾滋病毒有反应。47例对CLIA和NAT均有反应，6例仅对NAT有反应，6107例无反应。结论:本研究检测到的NAT收率为0.096%。(1:1039捐款)。提示NAT应作为血库筛查的首选方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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