Prevalence of Clostridioides difficile contamination in the healthcare environment and instruments: A systematic review and meta-analysis.

IF 1.7 Q3 INFECTIOUS DISEASES GERMS Pub Date : 2022-09-01 DOI:10.18683/germs.2022.1340
Soroush Borji, Mosayeb Rostamian, Sepide Kadivarian, Sara Kooti, Shirin Dashtbin, Somayeh Hosseinabadi, Ramin Abiri, Amirhooshang Alvandi
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Abstract

Introduction: Worldwide, Clostridioides difficile infection is becoming one of the most common healthcare-associated infections. Management and control of this infection in healthcare facilities are associated with screening for environmental and instrumental C. difficile contamination. This systematic review and meta-analysis aimed to assess the overall prevalence of C. difficile in hospital settings, medical devices, and instruments.

Methods: Four main databases, PubMed, Web of Science, Google Scholar, and Scopus, were searched using the keywords Clostridioides difficile, Clostridium difficile, C. difficile, clostridia, Clostridium spp., hospital environments, antibiotic associate colitis, intensive care unit, and ward in combination as a search strategy. The PRISMA checklist was used for selecting eligible studies.

Results: A total of 11 eligible articles published between 2012 and 2021 were included. The overall pooled prevalence of C. difficile in hospital environments was 14.9%. The highest and lowest prevalence were reported for India (51.1%) and the USA (1.6%), respectively. The highest prevalence was reported for beds (46.3%). A significant heterogeneity was seen between C. difficile prevalence in hospital environments in different samples. The highest and lowest prevalence was reported for floor corners (63.2%) and privacy curtains (1.4%), respectively.

Conclusions: In conclusion, hospitals' medical devices and environmental surfaces are considered a crucial source of Clostridioides difficile infection. In this regard, we strongly recommend revising and improving the cleaning and disinfection methods in hospitals and quality control of cleaning adequacy.

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医疗环境和仪器中艰难梭菌污染的患病率:系统回顾和荟萃分析。
在世界范围内,艰难梭菌感染正在成为最常见的卫生保健相关感染之一。卫生保健设施中这种感染的管理和控制与筛查环境和仪器艰难梭菌污染有关。本系统综述和荟萃分析旨在评估艰难梭菌在医院环境、医疗器械和仪器中的总体患病率。方法:以clostridiides difficile、Clostridium difficile、C. difficile、clostridia、Clostridium spp、医院环境、抗生素相关性结肠炎、重症监护病房、联合病房为检索策略,对PubMed、Web of Science、Google Scholar、Scopus 4个主要数据库进行检索。使用PRISMA检查表选择符合条件的研究。结果:共纳入2012 - 2021年间发表的11篇符合条件的文章。医院环境中艰难梭菌的总流行率为14.9%。发病率最高和最低的分别是印度(51.1%)和美国(1.6%)。据报道,床的患病率最高(46.3%)。不同样本中艰难梭菌在医院环境中的患病率存在显著的异质性。据报告,最高和最低患病率分别为地板角(63.2%)和隐私窗帘(1.4%)。结论:医院医疗器械和环境表面是难辨梭菌感染的重要来源。在这方面,我们强烈建议修订和改进医院的清洁和消毒方法,以及清洁充分性的质量控制。
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来源期刊
GERMS
GERMS INFECTIOUS DISEASES-
CiteScore
2.80
自引率
5.00%
发文量
36
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