Massive Elevation of CA-125 in Chylous Ascites.

Abstract

555 Chylous ascites is a rare condition in children characterized by leakage of triglycerides and low density lipoprotein (LDL)-rich lymphatic fluid into the peritoneal cavity. Primary chylous disorders are most frequently caused by congenital lymphatic dysplasias or lymphatic malformations. In the treatment strategy, it is essential to first drain the fluid with recurrent paracentesis, stop enteral nutrition, and start parenteral nutrition and then continue the nutrition with foods containing medium-chain fatty acids.1,2 CA-125 is a high-molecularweight glycoprotein, originating from the coelomic epithelium. It is elevated in the majority of patients with epithelial ovarian cancer. It has also been shown to be elevated in lymphoma, leukemia, and gastrointestinal system malignancies.3-5 In this paper, it was aimed to present a child with isolated chylous ascites and CA-125 elevation without any malignancy or additional disease.