Calcium Carbonate as a Potential Intervention to Prevent Labor Dystocia: Narrative Review of the Literature.

IF 1.6 Q3 HEALTH CARE SCIENCES & SERVICES Journal of Patient-Centered Research and Reviews Pub Date : 2023-01-01 DOI:10.17294/2330-0698.2010
Sabahat Raees, Marie Forgie, Rita Mitchell, Emily Malloy
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Abstract

Anecdotally, there are attestations from clinicians of calcium carbonate being used successfully for laboring people experiencing labor dystocia. The goal of this narrative review was to provide a synopsis of pertinent literature on calcium use in obstetrics to explore the potential benefit of calcium carbonate as a simple and low-cost intervention for prevention or treatment of labor dystocia. To answer how calcium and carbonate physiologically contribute to myometrium contractility, we conducted a literature search of English-language peer-reviewed articles, with no year limitation, consisting of the keywords "calcium," "calcium carbonate," "calcium gluconate," "pregnancy," "hemorrhage," and variations of "smooth muscle contractility" and "uterine contractions." Though no overt evidence on calcium carbonate's ability to prevent labor dystocia was identified; relevant information was found regarding smooth muscle contractility, calcium's influence on uterine muscle contractility, and carbonate's potential impact on reducing amniotic fluid lactate levels to restore uterine contractility during labor. Studies reporting the potential effectiveness of calcium gluconate and sodium bicarbonate in preventing labor dystocia offer background, safety information, and rationale for a future randomized control trial to evaluate the ability of calcium carbonate to prevent labor dystocia and reduce rates of cesarean section.

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碳酸钙作为预防难产的潜在干预措施:文献综述。
有趣的是,有临床医生证明碳酸钙被成功地用于劳动人民经历难产。这篇叙述性综述的目的是提供有关钙在产科应用的相关文献摘要,以探讨碳酸钙作为一种简单和低成本的干预措施预防或治疗难产的潜在益处。为了回答钙和碳酸钙在生理上如何促进肌层收缩,我们对英文同行评审的文章进行了文献检索,没有年份限制,包括关键词“钙”、“碳酸钙”、“葡萄糖酸钙”、“怀孕”、“出血”以及“平滑肌收缩”和“子宫收缩”的变化。虽然没有明确的证据表明碳酸钙能够预防难产;我们发现了平滑肌收缩力、钙对子宫肌肉收缩力的影响以及碳酸盐对降低羊水乳酸水平以恢复分娩时子宫收缩力的潜在影响。研究报告了葡萄糖酸钙和碳酸氢钠预防难产的潜在有效性,为未来评估碳酸钙预防难产和降低剖宫产率的随机对照试验提供了背景、安全信息和基本原理。
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来源期刊
Journal of Patient-Centered Research and Reviews
Journal of Patient-Centered Research and Reviews HEALTH CARE SCIENCES & SERVICES-
自引率
5.90%
发文量
35
审稿时长
20 weeks
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