Hyaluronic Acid Fillers to Correct Cleft Lip Asymmetry in Adults: Description of Technique and Patient Reported Outcome Measure Using CLEFT-Q.

IF 1.2 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Cleft Palate-Craniofacial Journal Pub Date : 2024-11-01 Epub Date: 2023-07-24 DOI:10.1177/10556656231190532

Richard M Thomson, Thomas H Jovic, Charlotte Eckhardt, Tomás O'Neill

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Abstract

Objective: To determine the efficacy of hyaluronic acid (HLA) lip filler to correct subtle cleft lip asymmetries in adults using a validated patient reported outcome measure (PROM).

Design: Prospective cross sectional.

Setting: UK National Health Service.

Patients, participants: Over 18 years old with repaired cleft lip and dissatisfaction of their lip appearance.

Interventions: HLA lip filler injection.

Main outcome measures: A validated, cleft specific PROM, the lip module of CLEFT-Q™ prior to treatment and again after six weeks.

Results: 24 patients included. A mean total CLEFT-Q™ score pre-procedure was 14.9 (Stand deviation (SD) = 4.91) and 24 (SD = 6.08) post-procedure. Difference in mean total score pre- and post-procedure were statically significant (P = .0001) in all domains on the CLEFT-Q™. No adverse outcomes.

Conclusion: HLA filler to correct subtle cleft lip asymmetries in adults is a simple low risk technique, which can significantly improve the patient's perception of lip appearance.

Conclusion: HLA lip filler to correct subtle cleft lip asymmetries in adults is a simple technique, low risk procedure which can significantly improve the patient's perception of lip appearance.

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透明质酸填充剂矫正成人唇裂不对称：使用 CLEFT-Q 对技术和患者报告结果测量进行描述。

目的使用经过验证的患者报告结果测量法（PROM），确定透明质酸（HLA）唇部填充剂矫正成人微小唇裂不对称的疗效：前瞻性横断面研究：患者、参与者干预措施：注射 HLA 唇部填充剂：主要结果测量：结果：共纳入 24 名患者。术前 CLEFT-Q™ 平均总分为 14.9（标准差 (SD) = 4.91），术后为 24（标准差 = 6.08）。手术前和手术后的平均总分差异在 CLEFT-Q™ 的所有领域均有统计学意义（P = .0001）。无不良反应：用 HLA 填充剂矫正成人细微的唇裂不对称是一种简单、低风险的技术，可显著改善患者对唇部外观的感知：用 HLA 唇部填充物矫正成人微小的唇裂不对称是一项技术简单、风险低的手术，可显著改善患者对唇部外观的感知。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cleft Palate-Craniofacial Journal 医学-外科

CiteScore

2.70

自引率

36.40%

发文量

215

期刊介绍： The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.