Vaccination against human papilloma virus in a Northeastern Italian area.

IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Annali dell'Istituto superiore di sanita Pub Date : 2023-07-01 DOI:10.4415/ANN_23_03_09
Francesca Valent, Laura Deroma, Giulia Degani
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Abstract

Objectives: Vaccination against human papilloma virus (HPV) in adolescents and persons at increased risk of infection and related consequences is an effective strategy to prevent genital cancers. The objective of this study was to assess vaccination activity and coverages in a Northeastern Italian area.

Methods: Anonymous data from various health administrative databases of the Italian 530,000-inhabitant Health Authority "Azienda Sanitaria Universitaria Friuli Centrale" were deterministically linked at the individual level through an anonymous stochastic key. Doses of HPV vaccine administered by year and coverages in different birth cohorts were calculated. Vaccinations of women treated for a CIN2+ lesion were also identified.

Results: The number of doses administered by year followed the evolution of national and regional laws. A steep drop was observed in 2020 and 2021 in both males and females (from 6,907 in 2019 to 5,027 in 2020 in males and from 6,989 in 2019 to 4,348 in 2020 in females). Coverages in adolescents were variable across Vaccination Services located in different sub-areas (complete cycle coverage in the 2008 cohort ranged from <40% in some Districts to >70% in others). Vaccination doses administered in adult women have increased almost steadily since 2018. One third of women treated for a CIN2+ were vaccinated.

Conclusions: In this area, efforts must be done to catch-up with doses missed during the pandemic and to overcome differences among different sub-areas.

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意大利东北部地区的人类乳头状瘤病毒疫苗接种。
目的:在感染风险和相关后果增加的青少年和人群中接种人类乳头状瘤病毒(HPV)疫苗是预防生殖器癌的有效策略。本研究的目的是评估意大利东北部地区的疫苗接种活动和覆盖率。方法:来自意大利53万居民卫生局“Azienda Sanitaria Universitaria Friuli Centrale”的各种卫生管理数据库的匿名数据通过匿名随机密钥在个人层面上进行确定性链接。计算了不同出生队列中按年份和覆盖范围接种的HPV疫苗的剂量。还确定了接受CIN2+病变治疗的妇女的疫苗接种情况。结果:每年给药的剂量遵循国家和地区法律的演变。2020年和2021年,男性和女性的人数都急剧下降(男性从2019年的6907人下降到2020年的5027人,女性从2019年到2020年,从6989人下降到4348人)。不同分区的疫苗接种服务机构的青少年覆盖率各不相同(2008年队列的全周期覆盖率从其他地区的70%不等)。自2018年以来,成年女性的疫苗接种剂量几乎稳步增加。三分之一接受CIN2+治疗的女性接种了疫苗。结论:在这一领域,必须努力弥补疫情期间错过的剂量,并克服不同子领域之间的差异。
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来源期刊
Annali dell'Istituto superiore di sanita
Annali dell'Istituto superiore di sanita PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
3.80
自引率
4.80%
发文量
65
审稿时长
>12 weeks
期刊介绍: Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews. The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office. The journal is in English.
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