Intraprocedural Plaque Protrusion during Carotid Artery Stenting with a CASPER Stent: A Case Report.

Takeshi Wada, Katsutoshi Takayama, Kaoru Myouchin, Keisuke Oshima, Toshihiro Tanaka, Kimihiko Kichikawa
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Abstract

Objective: Plaque protrusion (PP) during carotid artery stenting (CAS) is considered to be associated with periprocedural ischemic stroke. A new double-layer micromesh stent, the CASPER stent (CS), was approved for use in Japan in 2020. The expectation is that this micromesh stent system will reduce the risk of PP, but we report a case of PP during CAS despite the use of a CS.

Case presentation: An 87-year-old man presented with left hemiparesis. MRI showed right brain infarction and angiography showed right internal carotid artery stenosis with thrombus. Follow-up angiography after medical treatment showed that thrombus disappeared. We therefore performed CAS for right internal carotid artery stenosis with unstable plaque. CAS was performed under local anesthesia with Mo.Ma Ultra and FilterWire EZ protection using a CS placed to sufficiently cover the stenotic region. Conservative post-dilatation was then performed. Intravascular ultrasonography (IVUS) after post-dilatation showed the presence of PP. A second CS was then added using the stent-in-stent technique. No postoperative neurological abnormalities were found and the patient was discharged without postoperative complications. No stroke or restenosis has been observed as of 16 months after CAS.

Conclusion: PP can occur even when CAS is performed using the CS for carotid artery stenosis with unstable plaque. The importance of checking for PP using IVUS is suggested.

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颈动脉支架置入术中斑块突出1例报告。
目的:颈动脉支架植入术中斑块突出(PP)被认为与围手术期缺血性卒中有关。一种新的双层微孔支架CASPER支架(CS)于2020年被批准在日本使用。期望这种微孔支架系统将降低PP的风险,但我们报告了一例尽管使用CS,但在CAS期间发生PP的病例。病例介绍:一名87岁男性,表现为左偏瘫。MRI显示右脑梗死,血管造影显示右颈内动脉狭窄伴血栓。药物治疗后随访血管造影显示血栓消失。因此,我们对伴有不稳定斑块的右侧颈内动脉狭窄进行了CAS。CAS在局麻下进行,使用Mo.Ma Ultra和FilterWire EZ保护,使用CS放置以充分覆盖狭窄区域。然后进行保守扩张。扩张后血管内超声检查(IVUS)显示存在PP。然后使用支架内支架技术添加第二次CS。术后未发现神经系统异常,出院时无术后并发症。截至CAS后16个月,未观察到卒中或再狭窄。结论:颈动脉狭窄伴不稳定斑块,CS行CAS时仍可发生PP。提出了用IVUS检查PP的重要性。
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