Ocular Findings Aid in Diagnosis of West Nile Virus.

Q3 Medicine Wisconsin Medical Journal Pub Date : 2023-07-01
Brandon K Winward, Justin L Gottlieb, Jonathan S Chang, Luke Bradbury, Nenita Maganti, Chintan Pathak, Benjamin J Fowler
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引用次数: 0

Abstract

Introduction: West Nile virus disease, which is endemic to the United States, is a rarely reported systemic infection that can be difficult to diagnose. Chorioretinitis is an uncommon manifestation of West Nile virus but has pathognomonic ocular findings that can aid in diagnosis.

Case presentation: A 66-year-old man presented with acute onset fever, chills, and dyspnea. He underwent an extensive but nondiagnostic workup during hospitalization. New visual complaints prompted ophthalmology consultation. Funduscopic examination showed macular hemorrhages and midperipheral chorioretinal lesions. Fluorescein angiography revealed target-like lesions in a radial distribution, which is pathognomonic for West Nile virus chorioretinitis. Serology confirmed the diagnosis of West Nile virus disease. Systemic and ocular symptoms improved with supportive care.

Discussion: West Nile virus disease has many nonspecific manifestations. History of recent mosquito exposure is not always readily elicited. In patients with visual symptoms, eye examination can help in its diagnosis.

Conclusions: West Nile virus should be considered in patients with acute febrile or neurological illness during mosquito season.

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眼部表现有助于西尼罗病毒的诊断。
西尼罗河病毒病是美国的一种地方性疾病,是一种罕见的系统性感染,很难诊断。绒毛膜视网膜炎是西尼罗病毒的一种不常见的表现,但有病变的眼部发现,可以帮助诊断。病例介绍:一名66岁男性,表现为急性发热、寒战和呼吸困难。他在住院期间接受了广泛但非诊断性的检查。新的视力问题促使眼科咨询。眼底检查显示黄斑出血和中周绒毛膜视网膜病变。荧光素血管造影显示靶样病变呈放射状分布,这是西尼罗病毒脉络膜视网膜炎的典型病理特征。血清学确诊为西尼罗病毒病。系统和眼部症状在支持治疗后得到改善。讨论:西尼罗病毒病有许多非特异性表现。最近与蚊子接触的历史并不总是容易得到。对于有视觉症状的患者,眼部检查有助于诊断。结论:蚊虫季节急性发热或神经系统疾病患者应考虑西尼罗病毒感染。
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来源期刊
Wisconsin Medical Journal
Wisconsin Medical Journal Medicine-Medicine (all)
CiteScore
1.30
自引率
0.00%
发文量
72
期刊介绍: The Wisconsin Medical Society is the largest association of medical doctors in the state with more than 12,000 members dedicated to the best interests of their patients. With that in mind, wisconsinmedicalsociety.org offers patients a unique source for reliable, physician-reviewed medical information. The Wisconsin Medical Society has been a trusted source for health policy leadership since 1841.
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