Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD).

IF 2.1 4区医学 Q2 OTORHINOLARYNGOLOGY Acta Otorhinolaryngologica Italica Pub Date : 2023-08-01 DOI:10.14639/0392-100X-N2212

Arianna Cardella, Giuseppe Riva, Andrea Preti, Andrea Albera, Livio Luzi, Roberto Albera, Davide Cadei, Gian Marco Motatto, Filippo Omenetti, Giancarlo Pecorari, Francesco Ottaviani, Francesco Mozzanica

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Abstract

Objective: To evaluate the reliability and validity of the Italian version of the Brief Questionnaire of Olfactory Disorders (Brief-IT-QOD).

Methods: The study consisted of six phases: item generation, reliability analysis (112 dysosmic patients for internal consistency analysis and 61 for test-retest reliability analysis), normative data generation (303 normosmic subjects), validity analysis (comparison of Brief-IT-QOD scores of healthy and dysosmic subjects and scores correlation with psychophysical olfactory testing TDI and SNOT-22 scores), responsiveness analysis (10 dysosmic chronic rhinosinusitis with nasal polyps patients before and after biologic therapy), and cut-off value determination (ROC curve analysis of Brief-IT-QOD sensitivity and specificity).

Results: All subjects completed the Brief-IT-QOD. Internal consistency (α > 0.70) and test-retest reliability (ICC > 0.7) were acceptable and satisfactory for both questionnaire subscales. A significant difference between dysosmic and control subjects was found in both subscales (p < 0.05). Significant correlations between subscales scores and TDI and SNOT-22 scores were observed. Brief-IT-QOD scores before treatment were significantly higher than after biological therapy.

Conclusions: Brief-IT-QOD is reliable, valid, responsive to changes in QoL, and recommended for clinical practice and outcome research.

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意大利版嗅觉障碍简要问卷(Brief- it - qod)。

目的:评价意大利版嗅觉障碍简要问卷(Brief- it - qod)的信度和效度。方法:研究分为六个阶段:项目生成、信度分析(112例呼吸困难患者进行内部一致性分析，61例进行重测信度分析)、规范数据生成(303例正常受试者)、效度分析(健康受试者与呼吸困难受试者Brief-IT-QOD评分及与心理物理嗅觉测试TDI和SNOT-22评分的相关)、反应性分析(10例呼吸困难慢性鼻窦炎伴鼻息肉患者生物治疗前后)、截断值测定(Brief-IT-QOD敏感性和特异性的ROC曲线分析)。结果:所有受试者均完成了Brief-IT-QOD。两个量表的内部一致性(α > 0.70)和重测信度(ICC > 0.7)均可接受和满意。在这两个分量表中，运动障碍和控制组的差异均有统计学意义(p < 0.05)。各分量表得分与TDI和SNOT-22得分之间存在显著相关性。治疗前Brief-IT-QOD评分明显高于生物治疗后。结论:Brief-IT-QOD可靠、有效，对生活质量变化有反应，推荐用于临床实践和结局研究。

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来源期刊

Acta Otorhinolaryngologica Italica OTORHINOLARYNGOLOGY-

CiteScore

3.40

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Acta Otorhinolaryngologica Italica first appeared as “Annali di Laringologia Otologia e Faringologia” and was founded in 1901 by Giulio Masini. It is the official publication of the Italian Hospital Otology Association (A.O.O.I.) and, since 1976, also of the Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (S.I.O.Ch.C.-F.). The journal publishes original articles (clinical trials, cohort studies, case-control studies, cross-sectional surveys, and diagnostic test assessments) of interest in the field of otorhinolaryngology as well as clinical techniques and technology (a short report of unique or original methods for surgical techniques, medical management or new devices or technology), editorials (including editorial guests – special contribution) and letters to the Editor-in-Chief. Articles concerning science investigations and well prepared systematic reviews (including meta-analyses) on themes related to basic science, clinical otorhinolaryngology and head and neck surgery have high priority.