Gastric (gastrointestinal)-type endometrial adenocarcinoma presenting as a solitary endometrial polyp: a case report and literature review on a novel and potentially aggressive endometrial cancer histotype.

IF 4.4 Q1 PATHOLOGY PATHOLOGICA Pub Date : 2023-08-01 DOI:10.32074/1591-951X-870
Emma Bragantini, Giuseppe Angelico, Maria Giulia Disanto, Elena Magri, Livia Maccio, Mattia Barbareschi
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引用次数: 0

Abstract

Gastric-type carcinoma of the endometrium is a rare endometrial cancer histotype, recently introduced in the 2020 WHO classification of the female genital tract tumors. Clinico-pathological features, as well as treatment strategies for this rare histotype, are not fully defined. We herein present an unusual case of endometrial carcinoma with mucinous features arising in a 58-year-old menopausal woman. Morphological features of the present case as well as immunohistochemical profile were consistent with gastrointestinal differentiation. Therefore, after clinical and imaging studies ruled out the possibility of a metastatic origin, a final diagnosis of gastric-type carcinoma of the endometrium was rendered.

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胃(胃肠)型子宫内膜腺癌表现为孤立的子宫内膜息肉:一种新型且具有潜在侵袭性的子宫内膜癌组织型的病例报告和文献综述。
胃型子宫内膜癌是一种罕见的子宫内膜癌组织类型,最近在2020年WHO中引入了女性生殖道肿瘤的分类。临床病理特征,以及这种罕见的组织类型的治疗策略,还没有完全确定。我们在此报告一例罕见的子宫内膜癌与粘液特征出现在一个58岁的绝经妇女。本病例的形态学特征以及免疫组织化学特征与胃肠道分化一致。因此,在临床和影像学检查排除转移起源的可能性后,最终诊断为子宫内膜胃型癌。
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来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
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