Occupational Evaluation of Federal Highway Police Officers Exposed to Cholinesterase Inhibiting Insecticides.

IF 1.4 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Occupational and Environmental Medicine Pub Date : 2023-10-01 Epub Date: 2023-07-31 DOI:10.1097/JOM.0000000000002937

Juliandra Spagnol Bonache, Bruna Francisquete Costa, Marcio Tadashi Hoshino, Larissa Ludwig, Marcos Aurélio Barboza de Oliveira, Guilherme Luz Emerick

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Abstract

Objective: The aim of this study is to evaluate the effects of occupational exposure of federal highway police (PRF) officers to cholinesterase-inhibiting insecticides.

Methods: We evaluate erythrocyte and plasma cholinesterase activity, pulse rate, systolic and diastolic pressure, and clinical evaluation through the Mini-Mental State Examination and the Diagnostic and Statistical Manual of Mental Disorders , Fifth Edition .

Results: All PRF officers evaluated were male, between 22 and 49 years of age. Pulse rate of the subjects were statistically superior in the post-exposure moment when compared with pre-exposure moment. Inhibition of acetylcholinesterase and butyrylcholinesterase was significant in the post-exposure moment when compared with pre-exposure moment.

Conclusions: The results of the present work show that there are significant biochemical changes, which can be the beginning of serious deleterious effects to the health of PRF officers.

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接触胆碱酯酶抑制剂杀虫剂的联邦公路警察的职业评估。

目的：本研究旨在评估联邦公路警察（PRF）官员职业接触胆碱酯酶抑制剂的影响。方法：我们通过迷你精神状态检查和《精神障碍诊断与统计手册》（第五版）评估红细胞和血浆胆碱酯酶活性、脉搏率、收缩压和舒张压以及临床评估。结果：所有接受评估的PRF官员均为男性，年龄在22至49岁之间。与暴露前相比，受试者在暴露后的脉搏率在统计学上更高。与暴露前相比，暴露后对乙酰胆碱酯酶和丁酰胆碱酯酶的抑制作用显著。结论：目前的工作结果表明，存在显著的生化变化，这可能是对PRF官员健康产生严重有害影响的开始。

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来源期刊

Journal of Occupational and Environmental Medicine 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

9.40%

发文量

402

审稿时长

3-8 weeks

期刊介绍： Journal of Occupational and Environmental Medicine is an indispensable guide to good health in the workplace for physicians, nurses, and researchers alike. In-depth, clinically oriented research articles and technical reports keep occupational and environmental medicine specialists up-to-date on new medical developments in the prevention, diagnosis, and rehabilitation of environmentally induced conditions and work-related injuries and illnesses.