Christopher M. Bartley MD, PhD, Thomas T. Ngo BS, Le Duy Do PhD, Anastasia Zekeridou MD, PhD, Ravi Dandekar BS, MS, Sergio Muñiz-Castrillo MD, PhD, Bonny D. Alvarenga BA, Kelsey C. Zorn BA, MHS, Asritha Tubati BS, Anne-Laurie Pinto MSc, Weston D. Browne BS, Patrick W. Hullett MD, PhD, Mark Terrelonge MD, MPH, Ryan D. Schubert MD, Amanda L. Piquet MD, Binxia Yang PhD, Mayra Montalvo MD, Andrew F. Kung BA, Sabrina A. Mann BS, Maulik P. Shah MD, MHS, Michael D. Geschwind MD, PhD, Jeffrey M. Gelfand MD, MAS, Joseph L. DeRisi PhD, Sean J. Pittock MD, Jérôme Honnorat MD, PhD, Samuel J. Pleasure MD, PhD, Michael R. Wilson MD, MAS
{"title":"Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins","authors":"Christopher M. Bartley MD, PhD, Thomas T. Ngo BS, Le Duy Do PhD, Anastasia Zekeridou MD, PhD, Ravi Dandekar BS, MS, Sergio Muñiz-Castrillo MD, PhD, Bonny D. Alvarenga BA, Kelsey C. Zorn BA, MHS, Asritha Tubati BS, Anne-Laurie Pinto MSc, Weston D. Browne BS, Patrick W. Hullett MD, PhD, Mark Terrelonge MD, MPH, Ryan D. Schubert MD, Amanda L. Piquet MD, Binxia Yang PhD, Mayra Montalvo MD, Andrew F. Kung BA, Sabrina A. Mann BS, Maulik P. Shah MD, MHS, Michael D. Geschwind MD, PhD, Jeffrey M. Gelfand MD, MAS, Joseph L. DeRisi PhD, Sean J. Pittock MD, Jérôme Honnorat MD, PhD, Samuel J. Pleasure MD, PhD, Michael R. Wilson MD, MAS","doi":"10.1002/ana.26776","DOIUrl":null,"url":null,"abstract":"Co‐occurring anti‐tripartite motif‐containing protein 9 and 67 autoantibodies (TRIM9/67‐IgG) have been reported in only a very few cases of paraneoplastic cerebellar syndrome. The value of these biomarkers and the most sensitive methods of TRIM9/67‐IgG detection are not known.","PeriodicalId":127,"journal":{"name":"Annals of Neurology","volume":"94 6","pages":"1086-1101"},"PeriodicalIF":8.1000,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ana.26776","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Neurology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ana.26776","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Co‐occurring anti‐tripartite motif‐containing protein 9 and 67 autoantibodies (TRIM9/67‐IgG) have been reported in only a very few cases of paraneoplastic cerebellar syndrome. The value of these biomarkers and the most sensitive methods of TRIM9/67‐IgG detection are not known.
期刊介绍：
Annals of Neurology publishes original articles with potential for high impact in understanding the pathogenesis, clinical and laboratory features, diagnosis, treatment, outcomes and science underlying diseases of the human nervous system. Articles should ideally be of broad interest to the academic neurological community rather than solely to subspecialists in a particular field. Studies involving experimental model system, including those in cell and organ cultures and animals, of direct translational relevance to the understanding of neurological disease are also encouraged.
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