Diastolic Blood Pressure and Cognitive Functioning: Differences by Systolic Blood Pressure Among US Adults.

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY American Journal of Alzheimers Disease and Other Dementias Pub Date : 2023-01-01 DOI:10.1177/15333175231172283

A Mathew, R A Mesa, L Nahodyl, J Tremblay, T Rundek, A Zeki Al Hazzouri, T Elfassy

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Abstract

Background: The role of diastolic blood pressure (DBP) with cognitive functioning is under-explored in relation to levels of systolic blood pressure (SBP).

Methods: We studied 5466 participants from the National Health and Nutrition Examination Survey. Blood pressure was measured 3 times manually with a standardized sphygmomanometer and averaged. Cognitive functioning was measured using the digit symbol substitution test (DSST).

Results: Participants were 60 years or older, 55% female, and 81% non-Hispanic White. Most participants had a DBP between 70 to <80 mmHg (33.7%), between 60 to <70 mmHg (29.3%), or <60 mmHg (18.8%). From multivariable linear regression analyses, each 5 mmHg increment of DBP was associated with significantly higher DSST scores among individuals with SBP <120 only (ß: 0.56, 95% CI: 0.09, 1.03).

Conclusions: Among older US adults, at non-elevated levels of SBP, higher DBP is associated with better cognitive performance.

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舒张压与认知功能：美国成年人收缩压的差异。

背景：舒张压（DBP）与认知功能的关系尚未得到充分研究：舒张压（DBP）与认知功能的作用与收缩压（SBP）水平的关系尚未得到充分探讨：我们研究了 5466 名来自美国国家健康与营养调查的参与者。使用标准血压计手动测量血压 3 次并取平均值。认知功能采用数字符号替换测试（DSST）进行测量：参与者年龄在 60 岁或以上，55% 为女性，81% 为非西班牙裔白人。大多数参与者的 DBP 在 70 到结论之间：在美国老年人中，在 SBP 不升高的情况下，DBP 越高，认知能力越好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).