[Epidemiological Panorama of Cervical Dysplasia in a First-Level Care Unit].

Patricia Seefoó-Jarquín, Francisca Sosa-Jurado, Paola Maycotte-González
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Abstract

Background: Cervical cancer (CaCU) is the second cancer-related cause of death for women in Mexico. Early diagnosis and monitoring of patients by cervical cytology and colposcopy are currently the preferred screening methods for identification and prevention of this disease.

Objective: To describe the epidemiological panorama of cervical dysplasia diagnosed in a first-level care hospital.

Methods: The study was observational, retrospective, unicentric, homodemic, transversal. Records from 6,207 women who attended the General Subzone Hospital with Familiar Medicine #8 (HGSZ/UMF 8), in Tlaxcala, Mexico were analyzed. First-time cervical cytologies were analyzed from 2019 to 2021.

Results: Cervical dysplasia was found in 2.6% of the patients being the most frequent type of dysplasia NIC 1. Most of the clinical characteristics of patients with dysplasia were in agreement with those of the Mexican population. Important differences were found (comorbilities, mass index, number of sexual partners, births, positivity to changes related to HPV and vaccination) between two population sets defined by age (younger and older than 40 years).

Conclusions: The only factor where a tendency to be associated to type 2 and 3 dysplasia in the population younger than 40 years was the sexually active onset of life younger than 18 years, so this possible association should be evaluated in a bigger population. Our data suggests that risks factors should be evaluated separately for these age groups due to important differences regarding their clinic and epidemiological characteristics as well as changes in risk factor exposure.

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[一级护理单位宫颈发育不良的流行病学全景图]。
背景:宫颈癌(CaCU)是墨西哥妇女死亡的第二大癌症相关原因。通过宫颈细胞学检查和阴道镜检查对患者进行早期诊断和监测是目前识别和预防本病的首选筛查方法。目的:描述某一级护理医院诊断的宫颈发育不良的流行病学概况。方法:采用观察性、回顾性、单中心、同源性、横向研究。分析了墨西哥特拉斯卡拉通用分区医院(HGSZ/UMF 8) 6207名妇女的记录。分析2019年至2021年首次宫颈细胞学检查。结果:宫颈发育不良发生率为2.6%,为最常见的异型增生类型NIC 1。大多数不典型增生患者的临床特征与墨西哥人群一致。发现了重要的差异(合并症、质量指数、性伴侣数量、出生、对HPV和疫苗接种相关变化的阳性反应),这是由年龄(年轻和40岁以上)定义的两个人群组之间的差异。结论:在年龄小于40岁的人群中,与2型和3型发育不良相关的唯一因素是年龄小于18岁的性生活开始活跃,因此这种可能的关联应该在更大的人群中进行评估。我们的数据表明,由于这些年龄组的临床和流行病学特征以及危险因素暴露的变化存在重要差异,因此应分别评估这些年龄组的危险因素。
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