Association between averaged intraoperative nociceptive response index and postoperative complications after lung resection surgery.

IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Interactive cardiovascular and thoracic surgery Pub Date : 2022-11-08 DOI:10.1093/icvts/ivac258
Takuma Okamoto, Yuka Matsuki, Hiroki Ogata, Hiroai Okutani, Ryusuke Ueki, Nobutaka Kariya, Tsuneo Tatara, Munetaka Hirose
{"title":"Association between averaged intraoperative nociceptive response index and postoperative complications after lung resection surgery.","authors":"Takuma Okamoto,&nbsp;Yuka Matsuki,&nbsp;Hiroki Ogata,&nbsp;Hiroai Okutani,&nbsp;Ryusuke Ueki,&nbsp;Nobutaka Kariya,&nbsp;Tsuneo Tatara,&nbsp;Munetaka Hirose","doi":"10.1093/icvts/ivac258","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Since postoperative complications, defined as Clavien-Dindo grade ≥II, correlate with long-term survival after lung resection surgery in patients with primary lung cancer, identification of intraoperative risk factors for postoperative complications is crucial for better perioperative management. In the present study, we investigated the possible association between intraoperative variables for use in anaesthetic management and Clavien-Dindo grade ≥II.</p><p><strong>Methods: </strong>In this multi-institutional observational study, consecutive adult patients undergoing video-assisted thoracic surgery for primary lung cancer under general anaesthesia from March 2019 to April 2021 were enrolled. All patients were divided into 2 groups with Clavien-Dindo grade <II and ≥II. Uni- and multivariable analyses were performed to identify intraoperative risk factors.</p><p><strong>Results: </strong>After univariable analysis between patients with Clavien-Dindo grade <II (n = 415) and ≥II (n = 121), multivariable analysis revealed higher averaged nociceptive response (NR) index during surgery (mean NR), male sex, lower body mass index, longer duration of surgery, higher blood loss and lower urine volume, as independent risk factors for postoperative complications. In sensitivity analysis, based on the cut-off value of mean NR for postoperative complications, all patients were divided into high and low mean NR groups. The incidence of postoperative complications was significantly higher in patients with high mean NR (n = 332) than in patients with low mean NR (n = 204; P < 0.001).</p><p><strong>Conclusions: </strong>Higher mean NR, as intraoperative variables for use in anaesthetic management, is associated with the higher incidence of postoperative complications after primary lung cancer surgery.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725181/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interactive cardiovascular and thoracic surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/icvts/ivac258","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 1

Abstract

Objectives: Since postoperative complications, defined as Clavien-Dindo grade ≥II, correlate with long-term survival after lung resection surgery in patients with primary lung cancer, identification of intraoperative risk factors for postoperative complications is crucial for better perioperative management. In the present study, we investigated the possible association between intraoperative variables for use in anaesthetic management and Clavien-Dindo grade ≥II.

Methods: In this multi-institutional observational study, consecutive adult patients undergoing video-assisted thoracic surgery for primary lung cancer under general anaesthesia from March 2019 to April 2021 were enrolled. All patients were divided into 2 groups with Clavien-Dindo grade

Results: After univariable analysis between patients with Clavien-Dindo grade

Conclusions: Higher mean NR, as intraoperative variables for use in anaesthetic management, is associated with the higher incidence of postoperative complications after primary lung cancer surgery.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
肺切除术后平均术中伤害反应指数与术后并发症的关系。
目的:由于术后并发症(定义为Clavien-Dindo分级≥II)与原发性肺癌患者肺切除术后的长期生存相关,因此识别术后并发症的术中危险因素对于更好地围手术期管理至关重要。在本研究中,我们调查了术中用于麻醉管理的变量与Clavien-Dindo分级≥II之间的可能关联。方法:在这项多机构观察性研究中,纳入了2019年3月至2021年4月在全身麻醉下接受电视辅助胸外科手术治疗原发性肺癌的连续成年患者。结果:Clavien-Dindo分级患者间的单变量分析结论:较高的平均NR作为麻醉管理的术中变量,与原发性肺癌手术后较高的术后并发症发生率相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Interactive cardiovascular and thoracic surgery
Interactive cardiovascular and thoracic surgery CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.30
自引率
0.00%
发文量
292
审稿时长
2-4 weeks
期刊介绍: Interactive CardioVascular and Thoracic Surgery (ICVTS) publishes scientific contributions in the field of cardiovascular and thoracic surgery, covering all aspects of surgery of the heart, vessels and the chest. The journal publishes a range of article types including: Best Evidence Topics; Brief Communications; Case Reports; Original Articles; State-of-the-Art; Work in Progress Report.
期刊最新文献
Local tumour residue after microwave ablation for lung cancer: a case report. Long-term outcomes of papillary muscle relocation anteriorly for functional mitral regurgitation. Postoperative aortic injury caused by a staple line formed during wedge resection of the lung. Surgical management of cardiac cystic echinococcosis in a paediatric patient: a case report. Congenital aortocaval fistula combined with patent ductus arteriosus in an infant: a case report.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1