Reduced thalamic activity in ADHD under ABR forward masking conditions.

IF 1.4 4区 心理学 Q4 CLINICAL NEUROLOGY Applied Neuropsychology: Child Pub Date : 2024-07-01 Epub Date: 2022-12-16 DOI:10.1080/21622965.2022.2155520
Johan Källstrand, Katalin Niklasson, Magnus Lindvall, Emma Claesdotter-Knutsson
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Abstract

Attention-deficit hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder characterized by symptoms of inattention, overactivity, and/or impulsiveness. The prevalence of ADHD varies in different settings and there have been voices raised to call for more objective measures in order to avoid over- and underdiagnosing of ADHD. Auditory Brainstem Response (ABR) is a method where click shaped sounds evoke potentials that are recorder from electrodes on the skull of a patient. The aim of this study was to explore possible alterations in the ABR of 29 patients with ADHD compared to 39 healthy controls. We used a forward masked sound. We found differences in ABR that correspond to the thalamic area. The thalamus seems to play an active role in regulation of activity level in ADHD. More research is needed to draw any further conclusions on using ABR as an objective measurement to detect ADHD.

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在 ABR 前向掩蔽条件下,多动症患者丘脑活动减少。
注意力缺陷多动障碍(ADHD)是一种常见的慢性神经发育障碍,以注意力不集中、过度活跃和/或冲动等症状为特征。注意力缺陷多动障碍的发病率在不同的环境中存在差异,因此有人呼吁采取更客观的测量方法,以避免对注意力缺陷多动障碍的过度诊断或诊断不足。听觉脑干反应(ABR)是一种通过患者头骨上的电极记录咔嗒声诱发电位的方法。本研究旨在探讨 29 名多动症患者的 ABR 与 39 名健康对照者相比可能发生的变化。我们使用了前向遮蔽声音。我们发现了与丘脑区域相对应的 ABR 差异。丘脑似乎在调节多动症患者的活动水平方面发挥着积极作用。使用 ABR 作为检测多动症的客观测量方法还需要更多的研究才能得出进一步的结论。
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来源期刊
Applied Neuropsychology: Child
Applied Neuropsychology: Child CLINICAL NEUROLOGY-PSYCHOLOGY
CiteScore
4.00
自引率
5.90%
发文量
47
期刊介绍: Applied Neuropsychology: Child publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in children. Full-length articles and brief communications are included. Case studies of child patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.
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