Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis.
{"title":"Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis.","authors":"Jiejing Zhao, Lihua Xia","doi":"10.1080/10641955.2022.2079674","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>We reviewed the association between hypertensive disorders of pregnancy (HDP) and the risk of attention-deficit/hyperactivity disorder (ADHD) in children.</p><p><strong>Methods: </strong>We searched the databases of PubMed, Embase, ScienceDirect, CENTRAL, and Google Scholar for studies.</p><p><strong>Results: </strong>Twelve studies were included. Meta-analysis demonstrated that history of HDP results in a statistically significant increased risk of ADHD. Subgroup analysis of cohort and case-control studies also yielded similar results. Pre-eclampsia and chronic hypertension were associated with a statistically significant increased risk of ADHD in the offspring but not pregnancy-induced hypertension.</p><p><strong>Conclusion: </strong>Exposure to HDP significantly increases the risk of ADHD in the offspring.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"41 3-4","pages":"149-158"},"PeriodicalIF":1.5000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hypertension in Pregnancy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10641955.2022.2079674","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: We reviewed the association between hypertensive disorders of pregnancy (HDP) and the risk of attention-deficit/hyperactivity disorder (ADHD) in children.
Methods: We searched the databases of PubMed, Embase, ScienceDirect, CENTRAL, and Google Scholar for studies.
Results: Twelve studies were included. Meta-analysis demonstrated that history of HDP results in a statistically significant increased risk of ADHD. Subgroup analysis of cohort and case-control studies also yielded similar results. Pre-eclampsia and chronic hypertension were associated with a statistically significant increased risk of ADHD in the offspring but not pregnancy-induced hypertension.
Conclusion: Exposure to HDP significantly increases the risk of ADHD in the offspring.
期刊介绍：
Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
