Clinical impact of COVID-19 on tuberculosis.

Q2 Medicine Infezioni in Medicina Pub Date : 2022-12-01 eCollection Date: 2022-01-01 DOI:10.53854/liim-3004-3
Stefano Sanduzzi Zamparelli, Mauro Mormile, Alessandro Sanduzzi Zamparelli, Amedeo Guarino, Roberto Parrella, Marialuisa Bocchino
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Abstract

During COVID-19 pandemic, a lot of diseases suffered from a limited access to health care services, owing to the use of resources, both technical and financial, mainly directed towards such a dramatic outbreak. Among these, tuberculosis (TB) has been one of the most penalized, with a huge delay both in diagnosis and in start of treatment, with a consequential dramatic increase in morbidity and mortality. COVID-19 and tuberculosis share similar common pathogenetic pathways, and both diseases affect primarily the lungs. About the impact of TB on COVID-19 severity and mortality, data are unclear and literature reports are often conflicting. Certainly, considering the management of coinfected patients, there are pharmacokinetic interactions between several drugs used for the therapy of SARS-CoV-2 infection and the treatment of TB.

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COVID-19 对结核病的临床影响。
在 COVID-19 大流行期间,由于技术和财政资源的使用主要是为了应对如此严重的疫情, 许多疾病的医疗服务受到限制。其中,肺结核(TB)是受影响最严重的疾病之一,无论是诊断还是开始治疗都出现了严重的延误,导致发病率和死亡率急剧上升。COVID-19 和肺结核有着相似的共同致病途径,而且这两种疾病都主要影响肺部。关于结核病对 COVID-19 严重程度和死亡率的影响,目前尚无明确数据,文献报道也往往相互矛盾。当然,考虑到对合并感染患者的管理,用于治疗 SARS-CoV-2 感染的几种药物与治疗结核病的药物之间存在药代动力学相互作用。
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来源期刊
Infezioni in Medicina
Infezioni in Medicina Medicine-Infectious Diseases
CiteScore
8.40
自引率
0.00%
发文量
62
期刊介绍: The Journal publishes original papers, in Italian or in English, on topics concerning aetiopathogenesis, prevention, epidemiology, diagnosis, clinical features and therapy of infections, whose acceptance is subject to the referee’s assessment. The Journal is of interest not only to infectious disease specialists, microbiologists and pharmacologists, but also to internal medicine specialists, paediatricians, pneumologists, and to surgeons as well. The Editorial Board includes experts in each of the above mentioned fields.
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