Medication Adherence of Persons with Type 2 Diabetes in Malaysia: A Scoping Review and Meta-Analysis.

IF 0.6 Q4 ENDOCRINOLOGY & METABOLISM Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2022-01-01 DOI:10.15605/jafes.037.01.14

Cheong Lieng Teng, Chun Wai Chan, Pei Se Wong

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引用次数: 2

Abstract

Objective: This is a scoping review of Malaysian scientific studies on medication adherence among persons with type 2 diabetes mellitus (T2DM).

Methodology: We conducted a bibliographic search of PubMed, Scopus and Google Scholar using the following keywords: "medication adherence," "drug compliance," "DMTAC" and "Malaysia." The search covered all publications up to 31 December 2021. Eligible articles were original studies conducted in Malaysia that measured or quantified medication adherence among persons with T2DM.

Results: We identified 64 eligible studies published between 2008 to 2021. Most studies included patients with T2DM in ambulatory facilities. Five studies were qualitative research. The quantitative research publications included clinical trials, and cross-sectional, validation, retrospective and prospective cohort studies. Thirty-eight studies used medication adherence scales. The Morisky Medication Adherence Scale (MMAS-8, used in 20 studies) and Malaysian Medication Adherence Scale (MALMAS, used in 6 studies) were the most commonly used tools. There were 6 validation studies with 4 medication adherence scales. A meta-analysis of 10 studies using MMAS-8 or MALMAS revealed that the pooled prevalence of low medication adherence is 34.2% (95% CI: 27.4 to 41.2, random effects model). Eighteen publications evaluated various aspects of the Diabetes Medication Therapy Adherence Clinics (DMTAC).

Conclusion: This scoping review documented extensive research on medication adherence among persons with diabetes in Malaysia. The quantitative meta-analysis showed a pooled low medication adherence rate.

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马来西亚2型糖尿病患者的药物依从性:范围回顾和荟萃分析。

目的:这是对马来西亚2型糖尿病(T2DM)患者药物依从性科学研究的范围综述。方法:我们使用以下关键词对PubMed、Scopus和Google Scholar进行了文献检索:“药物依从性”、“药物依从性”、“DMTAC”和“马来西亚”。检索涵盖截至2021年12月31日的所有出版物。符合条件的文章是在马来西亚进行的测量或量化T2DM患者药物依从性的原始研究。结果:我们确定了2008年至2021年间发表的64项符合条件的研究。大多数研究包括住院的2型糖尿病患者。5项研究为定性研究。定量研究出版物包括临床试验、横断面、验证、回顾性和前瞻性队列研究。38项研究使用了药物依从性量表。Morisky药物依从性量表(MMAS-8，在20项研究中使用)和马来西亚药物依从性量表(MALMAS，在6项研究中使用)是最常用的工具。共有6项验证研究和4种药物依从性量表。一项使用MMAS-8或MALMAS的10项研究的荟萃分析显示，低药物依从性的总患病率为34.2% (95% CI: 27.4至41.2，随机效应模型)。18篇出版物评估了糖尿病药物治疗依从性诊所(DMTAC)的各个方面。结论:本综述记录了马来西亚糖尿病患者药物依从性的广泛研究。定量荟萃分析显示，患者的药物依从率较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the ASEAN Federation of Endocrine Societies ENDOCRINOLOGY & METABOLISM-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.