Concomitant ruxolitinib with cytarabine-based induction chemotherapy in secondary acute myeloid leukemia evolving from myeloproliferative neoplasm.

IF 2.3 Q2 HEMATOLOGY Blood Research Pub Date : 2023-09-30 Epub Date: 2023-08-25 DOI:10.5045/br.2023.2023136
Dong Hyun Kim, Ja Min Byun, Dong-Yeop Shin, Inho Kim, Sung-Soo Yoon, Youngil Koh
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引用次数: 0

Abstract

Age 62 74 Gender F M MPN type Essential thrombocythemia Polycythemia vera AML diagnosis Feb 2019 Mar 2019 JAK2 status Negative Positive Other molecular status Complex karyotype, TP53, ROS1, FGFR4 mutations Not assessed Treatment 5+2 induction chemotherapy with ruxolitinib 5+2 induction chemotherapy with ruxolitinib Response to induction Complete remission Partial remission Response to consolidation Not assessed (EOT) Not assessed (EOT) EOT reason Septic pneumonia Deteriorated condition Duration of response 3 months + 24 months + OS 3 months 24 months + Outcome Deceased Medically stable after EOT
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鲁索利替尼联合阿糖胞苷诱导化疗治疗由骨髓增生性肿瘤演变而来的继发性急性髓系白血病。
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Blood Research
Blood Research HEMATOLOGY-
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3.70
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64
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