Valproate Induced Hyperammonemic Encephalopathy.

Wajeeha Qayyum, Zaland Ahmed Yousafzai, Muhammad Shahid Iqbal, Sohail Khan, Qazi Kamran Amin, Ihtesham Shafiqs
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Abstract

Valproate is a commonly prescribed anticonvulsant drug. It has a potential to cause hyperammonemia even in the presence of normal liver function tests. This hyperammonemic state can lead to encephalopathy referred as Valproate induced hyperammonemic encephalopathy (VHE). Here we present a case of valproate induced hyperammonemic encephalopathy in a young male caused by initiation of valproate therapy.

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丙戊酸钠所致高氨血症脑病。
丙戊酸是一种常用的抗惊厥药。即使在肝功能检查正常的情况下,它也有可能引起高氨血症。这种高铵状态可导致脑病,称为丙戊酸诱导的高铵性脑病(VHE)。在这里,我们提出一个病例的丙戊酸诱导高氨血症脑病在一个年轻的男性引起的开始丙戊酸治疗。
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