Why Didn't You Walk Yesterday? Factors Associated With Slow Early Recovery After Adult Spinal Deformity Surgery.

IF 3 3区 医学 Q2 CLINICAL NEUROLOGY Global Spine Journal Pub Date : 2025-03-01 Epub Date: 2023-08-23 DOI:10.1177/21925682231197976
Gregory S Kazarian, Francis Lovecchio, Robert Merrill, John Clohisy, Bo Zhang, Jerry Du, Yusef Jordan, Anthony Pajak, Rachel Knopp, David Kim, Justin Samuel, Jonathan Elysee, Izzet Akosman, Pratyush Shahi, Mitchell Johnson, Frank J Schwab, Virginie Lafage, Han Jo Kim
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Abstract

Study design: This is a retrospective case-control study.

Objectives: The objectives of this study are to identify (1) risk factors for delayed ambulation following adult spinal deformity (ASD) surgery and (2) complications associated with delayed ambulation.

Methods: One-hundred and ninety-one patients with ASD who underwent posterior-only fusion (≥5 levels, LIV pelvis) were reviewed. Patients who ambulated with physical therapy (PT) on POD2 or later (LateAmb, n = 49) were propensity matched 1:1 to patients who ambulated on POD0-1 (NmlAmb, n = 49) based on the extent of fusion and surgical invasiveness score (ASD-S). Risk factors, as well as inpatient medical complications were compared. Logistic regressions were used to identify risk factors for late ambulation.

Results: Of the patients who did not ambulate on POD0-1, 32% declined participation secondary to pain or dizziness/fatigue, while 68% were restricted from participation by PT/nursing due to fatigue, inability to follow commands, nausea/dizziness, pain, or hypotension. Logistic regression showed that intraoperative estimated blood loss (EBL) >2L (OR = 5.57 [1.51-20.55], P = .010) was independently associated with an increased risk of delayed ambulation, with a 1.25 times higher risk for every 250 mL increase in EBL (P = .014). Modified 5-Item Frailty Index (mFI-5) was also independently associated with delayed ambulation (OR = 2.53 [1.14-5.63], P = .023). LateAmb demonstrated a higher hospital LOS (8.4 ± 4.0 vs 6.2 ± 2.6, P < .001). The LateAmb group trended toward an increase in medical complications on POD3+ (14.3% vs 26.5%, P = .210).

Conclusions: EBL demonstrates a dose-response relationship with risk for delayed ambulation. Delayed ambulation increases LOS and may impact medical complications.

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你昨天为什么没有走路?成人脊柱畸形手术后早期恢复缓慢的相关因素。
研究设计:这是一项回顾性病例对照研究:本研究的目的是确定(1)成人脊柱畸形(ASD)手术后延迟下床活动的风险因素和(2)与延迟下床活动相关的并发症:对接受后路融合术(≥5级,LIV骨盆)的191例ASD患者进行了回顾性研究。根据融合程度和手术侵袭性评分(ASD-S),将在POD2或之后接受物理治疗(PT)的患者(LateAmb,n = 49)与在POD0-1接受物理治疗的患者(NmlAmb,n = 49)进行1:1倾向匹配。对风险因素和住院医疗并发症进行了比较。采用逻辑回归法确定晚期下床活动的风险因素:在POD0-1没有下床活动的患者中,32%的患者因疼痛或头晕/疲劳而拒绝参与,68%的患者因疲劳、无法听从命令、恶心/头晕、疼痛或低血压而被PT/护理限制参与。逻辑回归显示,术中估计失血量(EBL)>2L(OR = 5.57 [1.51-20.55],P = .010)与延迟下床风险增加有独立关联,EBL 每增加 250 mL,风险增加 1.25 倍(P = .014)。改良五项虚弱指数(mFI-5)也与延迟下床活动独立相关(OR = 2.53 [1.14-5.63],P = .023)。LateAmb 组的住院时间较长(8.4 ± 4.0 vs 6.2 ± 2.6,P < .001)。晚期Amb组在POD3+的医疗并发症呈上升趋势(14.3% vs 26.5%,P = .210):结论:EBL与延迟下床活动的风险呈剂量-反应关系。延迟下床增加了住院时间,并可能影响医疗并发症。
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来源期刊
Global Spine Journal
Global Spine Journal Medicine-Surgery
CiteScore
6.20
自引率
8.30%
发文量
278
审稿时长
8 weeks
期刊介绍: Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).
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