Efficacy of Platelet Rich Plasma and Platelet Rich Fibrin for Direct Pulp Capping in Adult Patients with Carious Pulp Exposure- A Randomised Controlled Trial.

IF 1.6 Q3 DENTISTRY, ORAL SURGERY & MEDICINE European Endodontic Journal Pub Date : 2022-06-01 DOI:10.14744/eej.2021.04834
Shekar Shobana, Mahendran Kavitha, Narasimhan Srinivasan
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引用次数: 3

Abstract

Objective: This study evaluated the effectiveness of Platelet Rich Plasma (PRP), Platelet Rich Fibrin (PRF) and Mineral Trioxide Aggregate (MTA) as direct pulp capping materials in patients with carious pulp exposure using cone beam computed tomography.

Methods: This parallel, triple blinded, randomised trial was done on 30 permanent posterior teeth chosen as candidates for direct pulp capping based on stringent inclusion and exclusion criteria. The samples were allocated based on sequentially numbered opaque sealed envelope method into three groups: MTA, PRP and PRF for direct pulp capping. The treated teeth were restored with Glass Ionomer cement liner and light-cured resin composite. Patients were followed up for a period of 12 months. Statistical analyses were performed with statistical software SPSS version 25. Data were analysed for normality using Shapiro Wilk's test. Dentine bridge volume analysis across the groups were done using Kruskal Wallis test with the significance level at P=0.05. As the test revealed a significant difference, post hoc analysis was done with Dunn test.

Results: CBCT analysis revealed that the volume of dentine bridge formed by PRP and PRF was significantly higher than the volume of dentine bridge formed by MTA (P<0.001; CI: 90%). There was no significant difference in the efficacy between the three direct pulp capping agents based on clinical assessment. A total of 27 teeth (90%) showed positive response to pulp sensibility testing and evidence of dentine bridge formation in radiograph at 12 months. No adverse events were encountered.

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富血小板血浆和富血小板纤维蛋白对成年龋齿暴露患者直接盖髓的疗效-一项随机对照试验。
目的:利用锥形束计算机断层扫描评价富血小板血浆(PRP)、富血小板纤维蛋白(PRF)和三氧化二矿骨料(MTA)作为牙髓暴露患者直接盖髓材料的有效性。方法:根据严格的纳入和排除标准,对30颗永久后牙进行了平行、三盲、随机试验,作为直接髓盖的候选者。根据顺序编号的不透明密封信封法将样品分为MTA、PRP和PRF三组进行直接盖髓。采用玻璃离子水门铁衬里和光固化树脂复合材料修复。患者随访12个月。采用SPSS统计软件25进行统计分析。使用Shapiro Wilk检验对数据进行正态性分析。各组牙本质桥体积分析采用Kruskal Wallis检验,显著性水平P=0.05。由于试验结果显示差异显著,故采用Dunn检验进行事后分析。结果:CBCT分析显示,PRP和PRF形成的牙本质桥体积明显高于MTA (P
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来源期刊
European Endodontic Journal
European Endodontic Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.40
自引率
5.60%
发文量
25
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