Consensus on targeted drug therapy for spondyloarthritis.

Xinping Tian, Mengtao Li, Shengyun Liu, Xiaomei Leng, Qian Wang, Jiuliang Zhao, Yi Liu, Yan Zhao, Yizhi Zhang, Huji Xu, Jieruo Gu, Xiaofeng Zeng
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Abstract

Spondyloarthritis (SpA) is a group of chronic inflammatory diseases that predominantly involve the spine and/or peripheral joints. The clinical manifestations of SpA are highly heterogenous and complicated with various comorbidities. SpA is a disabling disease and adversely affects the quality of life of patients. Many new medications that target cytokines or pathways specific for the pathogenesis of SpA have been developed and they are becoming increasingly important in the treatment of SpA. However, identifying the target patient population and standardizing the usage of these drugs are critical issues in the clinical application of these "targeted therapeutic drugs". Under the leadership of National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), managed by Peking Union Medical College Hospital, the "Consensus on targeted drug therapy for spondyloarthritis" has been developed in collaboration with the Rheumatology and Immunology Physicians Committee, Chinese Medical Doctors Association, Rheumatology and Immunology Professional Committee, Chinese Association of Rehabilitation Medicine, and Chinese Research Hospital Association Rheumatology and Immunology Professional Committee. This consensus has been developed with evidence-based methodology and has followed the international standard for consensus development.

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脊椎关节炎靶向药物治疗的共识。
脊椎关节炎(SpA)是一组主要累及脊柱和/或周围关节的慢性炎症性疾病。SpA的临床表现是高度异质性和复杂的各种合并症。SpA是一种致残疾病,对患者的生活质量有不利影响。许多针对SpA发病机制的细胞因子或特异性途径的新药物已经开发出来,它们在SpA的治疗中变得越来越重要。然而,在这些“靶向治疗药物”的临床应用中,确定目标患者人群并规范这些药物的使用是关键问题。在北京协和医院国家皮肤免疫疾病临床研究中心的领导下,与风湿病与免疫医师专业委员会、中华医师协会、风湿病与免疫专业委员会、中华康复医学协会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中华医学会风湿病与免疫专业委员会、中国研究型医院协会风湿病与免疫学专业委员会。这一共识是以循证方法形成的,并遵循了形成共识的国际标准。
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