Expanded Demographics for the Tillaux Fracture in Patients Receiving Feminizing Hormone Therapy A Case Report.

Amy Birnbaum, John F Dankert, Cordelia Carter, Mara Karamitopoulos
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Abstract

We present the case of a transgender female patient who had been undergoing feminizing hormone therapy for several years and sustained a Tillaux fracture despite being older than the expected age range for females with this injury pattern. Despite work focused on understanding physeal closure, the molecular signals governing this phenomenon remain incompletely described. This case study illustrates that physeal closure may be delayed in patients undergoing sex hormone therapy with associated transitional fractures possibly occurring later than would be expected for the transitional gender. Additional work is necessary to clarify the direct effect of sex hormonal therapy on physeal homeostasis.

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在接受女性化激素治疗的患者中,Tillaux骨折的扩展人口统计报告1例。
我们报告了一名变性女性患者,她接受了数年的女性化激素治疗,尽管年龄超过了这种损伤模式的女性的预期年龄范围,但仍发生了Tillaux骨折。尽管工作集中在理解物理闭合,控制这一现象的分子信号仍然不完全描述。本病例研究表明,在接受性激素治疗的患者中,骨骺闭合可能会延迟,而相关的过渡性骨折可能比预期的过渡性骨折发生得晚。需要进一步的工作来阐明性激素治疗对生理稳态的直接影响。
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